[{"data":1,"prerenderedAt":768},["ShallowReactive",2],{"ch-en/blog/categories/":3,"ch-en/video-hub/categories/":63,"ch-en/blog/articles/muscle-not-just-kilos-why-body-composition-matters-when-you-lose-weight-on-glp-1":97,"ch-en/page-settings":292,"en/blog/authors/9bce9c6c-da14-4e75-bb28-cc5fa141f16f/blog-details/":767},{"weight-loss":4,"activity":10,"general-health":23,"nutrition":33,"mental-health":43,"sleep":53},{"uuid":5,"title":6,"full_slug":7,"alternates":8,"slug":9},"4657aaff-45db-4486-95c3-82f90ce3948e","Weight Loss","ch-en/blog/categories/weight-loss",[],"weight-loss",{"uuid":11,"title":12,"full_slug":13,"alternates":14,"slug":22},"d73a324c-d502-4faa-8482-b6fb3f09b191","Activity","ch-en/blog/categories/activity",[15],{"id":16,"name":12,"slug":17,"published":18,"full_slug":19,"is_folder":20,"parent_id":21},417185145,"bewegung",true,"ch-de/blog/categories/bewegung",false,417185121,"activity",{"uuid":24,"title":25,"full_slug":26,"alternates":27,"slug":32},"1c3560ed-2bc4-40b7-9bde-6afa66f82004","General Health","ch-en/blog/categories/general-health",[28],{"id":29,"name":25,"slug":30,"published":18,"full_slug":31,"is_folder":20,"parent_id":21},417185140,"allgemeine-gesundheit","ch-de/blog/categories/allgemeine-gesundheit","general-health",{"uuid":34,"title":35,"full_slug":36,"alternates":37,"slug":42},"3f9c7e2c-4a46-44f6-9301-3756471fbdfa","Nutrition","ch-en/blog/categories/nutrition",[38],{"id":39,"name":35,"slug":40,"published":18,"full_slug":41,"is_folder":20,"parent_id":21},417185147,"ernaehrung","ch-de/blog/categories/ernaehrung","nutrition",{"uuid":44,"title":45,"full_slug":46,"alternates":47,"slug":52},"dce6fbcd-7e31-472e-b87a-9e68d32ea856","Mental Health","ch-en/blog/categories/mental-health",[48],{"id":49,"name":45,"slug":50,"published":18,"full_slug":51,"is_folder":20,"parent_id":21},417185149,"mentale-gesundheit","ch-de/blog/categories/mentale-gesundheit","mental-health",{"uuid":54,"title":55,"full_slug":56,"alternates":57,"slug":62},"bb7ca4ee-009a-4ef7-bdf0-cbe98202e244","Sleep","ch-en/blog/categories/sleep",[58],{"id":59,"name":55,"slug":60,"published":18,"full_slug":61,"is_folder":20,"parent_id":21},417185158,"schlaf","ch-de/blog/categories/schlaf","sleep",{"impact-tools":64,"experts":70,"biomarkers":80,"Tests":89},{"uuid":65,"title":66,"full_slug":67,"alternates":68,"slug":69},"273283f5-2da3-42d2-9318-655e1de3f291","Impact tools","ch-en/video-hub/categories/impact-tools",[],"impact-tools",{"uuid":71,"title":72,"full_slug":73,"alternates":74,"slug":77},"87cb6b41-79ad-41f5-aadd-7c926200eedb","Experts","ch-en/video-hub/categories/experts",[75],{"id":76,"name":72,"slug":77,"published":18,"full_slug":78,"is_folder":20,"parent_id":79},546376110,"experts","ch-de/video-hub/categories/experts",546080423,{"uuid":81,"title":82,"full_slug":83,"alternates":84,"slug":87},"9e6c8683-7234-4f91-a4bd-660009940ff9","Biomarkers","ch-en/video-hub/categories/biomarkers",[85],{"id":86,"name":82,"slug":87,"published":18,"full_slug":88,"is_folder":20,"parent_id":79},546376104,"biomarkers","ch-de/video-hub/categories/biomarkers",{"uuid":90,"title":91,"full_slug":92,"alternates":93,"slug":91},"32715961-0365-4180-8a41-310058f9a8f4","Tests","ch-en/video-hub/categories/Tests",[94],{"id":95,"name":91,"slug":91,"published":18,"full_slug":96,"is_folder":20,"parent_id":79},546080526,"ch-de/video-hub/categories/Tests",{"data":98,"headers":270},{"story":99,"cv":252,"rels":253,"links":269},{"name":100,"created_at":101,"published_at":102,"updated_at":103,"id":104,"uuid":105,"content":106,"slug":235,"full_slug":236,"sort_by_date":192,"position":237,"tag_list":238,"is_startpage":20,"parent_id":239,"meta_data":192,"group_id":240,"first_published_at":241,"release_id":192,"lang":198,"path":192,"alternates":242,"default_full_slug":236,"translated_slugs":251},"Muscle, Not Just Kilos: Why Body Composition Matters When You Lose Weight on GLP-1","2026-07-10T08:47:47.462Z","2026-07-13T14:04:41.169Z","2026-07-13T14:04:41.185Z",196541101964060,"fbf9d11d-b679-4668-b802-2ca20934656d",{"_uid":107,"body":108,"meta":159,"title":100,"author":170,"component":209,"categories":210,"description":225,"publishedAt":226,"heroMobileImage":227,"heroDesktopImage":231},"b97db241-575c-4bc4-b8bd-f4744e6d060b",[109,113,116,131,134,137,148,151,154],{"_uid":110,"content":111,"component":112},"c23b2881-33ba-451d-94ea-fe11b463d464","## **The three things to remember**\n\n- Part of the weight you lose is fat-free mass (including muscle) — in studies, roughly **20–30%**. At the same time, the ratio of muscle to fat often improves.\n- Keeping muscle is **largely in your hands**: enough protein and regular resistance training make the biggest difference.\n- So it isn’t the number on the scale that counts, but **how** you lose weight — and only your body composition shows that.\n\nThe scale is a poor storyteller. It gives you a single number — but it can’t tell you whether you’ve lost fat or also broken down muscle. And that’s exactly the difference that matters when you lose weight on GLP-1: losing weight is not the same as losing it *well*.\n\nThis article looks at where things stand with **muscle loss on GLP-1**, what the research says — and, above all, what you can do yourself so that in the end you lose mainly fat and keep your muscle.\n\n## **Do you lose muscle when you lose weight on GLP-1?**\n\nShort answer: yes, some of it. Whenever you lose weight — whether through diet, surgery or GLP-1 — part of it always comes from **fat-free mass**, which includes muscle. In analyses of GLP-1 studies, that share sat at roughly **20 to 30 percent** of the weight lost \\[1\\].\n\nThat sounds like a lot at first. But two things round out the picture:\n\nFirst, the **ratio** often improves. In the DXA body-composition substudy of the STEP-1 trial, fat-free mass fell by around 10 percent — yet its *share* of total weight rose slightly, because considerably more **fat** was lost \\[1\\]. The body became leaner overall, not “more muscle-poor” in relative terms.\n\nSecond, and this is the genuinely good news: muscle loss depends **more on your behaviour than on the medication**. That’s where you can step in.\n\n## **Why does muscle mass matter so much in the first place?**\n\nMuscle isn’t just about looks. It’s your **metabolic engine**: more muscle mass means your body burns more energy even at rest. Lose a lot of muscle and your resting metabolic rate drops — which makes *keeping* the weight off harder (one reason crash diets so often end in the yo-yo effect).\n\nMuscle also underpins everyday strength, mobility, bone health and — especially from midlife onward — protection against age-related muscle loss. Low skeletal-muscle mass is linked to a roughly **57% higher risk of all-cause mortality** \\[2\\]. Keeping muscle is one of the most important factors in making your result **healthy and lasting**.\n\n## **The good news: keeping muscle is largely in your hands**\n\nHow much muscle mass you keep is largely up to you — through nutrition and training. The evidence here is reassuringly clear.\n\nRecent analyses (2025) show that combining GLP-1 treatment with strength training and adequate protein markedly reduces the share of weight lost as muscle — a big difference from “just eating less.”\n\nThe medication curbs your appetite — but it’s what you eat and how you move that saves your muscle.","blog-detail-markdown",{"_uid":114,"content":115,"component":112},"f52f4349-6b8c-4d62-937b-c00e2a8de7f5","## **How much protein — and what kind of training?**\n\nTwo levers, both well supported:\n\n**Protein.** During weight loss, your body needs an above-average amount of protein to hold on to muscle. Current recommendations for people on GLP-1 therapy sit at around **1.2 to 1.6 grams per kilogram of body weight per day** — toward the upper end while you’re losing weight. In practice that means **20–40 g of protein per meal**, spread across the day. Good sources include quark, eggs, pulses, fish, poultry or tofu.\n\nThere’s a catch: GLP-1 lowers your appetite — which is exactly when many people find it hard to eat enough protein. This is where a plan helps (and sometimes targeted supplementation).\n\n**Resistance training.** A protein-rich diet alone isn’t enough — muscle is truly preserved only when you pair it with **regular resistance training**. The rough recommendation: **at least 2–3 strength sessions per week**, plus some endurance work (a guideline of around 150 minutes per week). You don’t need to become a bodybuilder — regular training with your own body weight, resistance bands or dumbbells already makes a big difference.\n\n### ",{"_uid":117,"imageFit":118,"imageNew":119,"component":120,"description":121,"mobileImage":122,"desktopImage":127},"70ec09ce-7f83-4dcf-84d9-8fcfafc17df3","cover",[],"blog-detail-image-with-description","",{"id":123,"alt":121,"name":121,"focus":121,"title":121,"source":121,"filename":124,"copyright":121,"fieldtype":125,"meta_data":126,"is_external_url":20},197678656166254,"https://a.storyblok.com/f/103647/1200x1600/d0eeb21427/protein-training-mobile.png","asset",{},{"id":128,"alt":121,"name":121,"focus":121,"title":121,"source":121,"filename":129,"copyright":121,"fieldtype":125,"meta_data":130,"is_external_url":20},197678656239983,"https://a.storyblok.com/f/103647/2800x2000/bdb05a6e84/protein-training-desktop.png",{},{"_uid":132,"content":133,"component":112},"91a7e26a-5b28-4ced-93bf-a8d945de852a","## **Why the scale deceives you — and what to measure instead**\n\nIf the scale is all that counts, the most important part slips under the radar. Minus 6 kilos could mean: 6 kilos of fat gone (great) — or 4 kilos of fat and 2 kilos of muscle (not good). The number is the same; the health behind it is entirely different.\n\nWhat you really want to see is your **body composition**: how much **fat** you’re losing and how much **muscle mass** you’re keeping. A **muscle-fat analysis** makes that visible — turning “I hope I’m doing this right” into “I can see it in black and white.” That’s not only motivating; it also lets you adjust course early if too much muscle is being lost.",{"_uid":135,"content":136,"component":112},"7b35fbd9-c75f-4483-aef3-cb9c568763ea","## **How *care* supports your body composition**\n\nThat’s why a muscle-fat analysis is a fixed part of treatment at *care* — not a one-off gimmick, but **every month**:\n\n- A **baseline assessment at the start** shows your starting point.\n- After that, your body composition is measured **monthly** — fat and muscle separately, not just your weight.\n- In the **medical video consultation**, the results are discussed: nutrition and training tips, managing side effects and — if needed — adjusting your dose.\n- In the **App**, you follow your progress and see whether you’re on the right track.\n\nThe focus isn’t the scale, but a healthy, sustainable result — with medical support.\n\n**Want to know where you stand — and whether a supported treatment fits you?** Take the no-obligation **eligibility check**. If you’re eligible, *care*’s FMH medical team reviews your details — medically checked, no pressure. → [Check your eligibility](/ch-en/tests/medical-weight-loss)",{"_uid":138,"imageFit":118,"imageNew":139,"component":120,"description":121,"mobileImage":140,"desktopImage":144},"744607da-9ba7-4532-becc-1d28a64b9a59",[],{"id":141,"alt":121,"name":121,"focus":121,"title":121,"source":121,"filename":142,"copyright":121,"fieldtype":125,"meta_data":143,"is_external_url":20},197678655568227,"https://a.storyblok.com/f/103647/1200x1600/32bbf95be8/care-desktop-en-1.png",{},{"id":145,"alt":121,"name":121,"focus":121,"title":121,"source":121,"filename":146,"copyright":121,"fieldtype":125,"meta_data":147,"is_external_url":20},197678655801703,"https://a.storyblok.com/f/103647/2800x2000/47602a96a4/care-desktop-en.png",{},{"_uid":149,"content":150,"component":112},"455c07fb-5a9e-450f-b242-53169e59e0fc","## **In brief**\n\nWhen you lose weight on GLP-1 you do lose some muscle mass too — but how much is largely in your own hands. Enough protein and regular resistance training are the strongest levers, and looking at your **body composition** rather than just the scale is what makes the difference between “lighter” and “healthier.” Measure it, with medical support, and you don’t just lose weight — you lose it the right way.\n\n## **Frequently asked questions**\n\n**Do you inevitably lose muscle on GLP-1?** Part of the weight you lose is fat-free mass, but the muscle loss can be sharply limited with protein and resistance training. In studies that included training and adequate protein, muscle loss was correspondingly small.\n\n**How much protein should I eat per day?** As a guideline, around 1.2–1.6 g per kilogram of body weight per day — toward the upper end while losing weight — ideally spread across several meals. Your individual amount is something your doctor will discuss with you.\n\n**Is protein alone enough to keep muscle?** No. Protein works best together with regular resistance training (around 2–3 times per week).\n\n**Why does *care* measure muscle-fat analysis every month?** Because the scale alone doesn’t show whether you’re losing fat or muscle. The monthly measurement makes your progress visible and allows the treatment to be adjusted when needed.",{"_uid":152,"content":153,"component":112},"65ea0c41-1796-43fd-8355-ba260ca642a9","### \n\n### **Medical disclaimer**\n\n*This article is intended for general information and health education. It does not replace individual medical advice, diagnosis or treatment. Any prescription treatments mentioned are available only on a doctor’s prescription. If you have health concerns, please consult a doctor.*",{"_uid":155,"title":156,"content":157,"component":158},"c36bc18b-1cdf-468a-a844-f2241f9068fd","List of References","\\[1\\] Wilding JPH, et al. *Once-weekly semaglutide in adults with overweight or obesity (STEP 1).* N Engl J Med. 2021;384(11):989–1002. doi:[10.1056/NEJMoa2032183](https://doi.org/10.1056/NEJMoa2032183).\n\n\\[2\\] Low skeletal muscle mass index and all-cause mortality risk in adults: a systematic review and meta-analysis of prospective cohort studies. PLOS One. 2023. doi:[10.1371/journal.pone.0286745](https://doi.org/10.1371/journal.pone.0286745).","BlogDetailCollapsibleMarkdown",[160],{"_uid":161,"title":162,"no_index":20,"og_image":163,"canonical":164,"component":167,"no_follow":20,"description":168,"image_param":169,"hide_sitemap":20},"95269a16-d9b8-47b3-9cf0-6b89f0c1a6bb","GLP-1 & Muscle Loss: Body Composition, Not Just Scale","//a.storyblok.com/f/103647/2400x1200/6c0cf8ac49/meta-image.png",{"id":121,"url":121,"linktype":165,"fieldtype":166,"cached_url":121},"story","multilink","meta","Do you lose muscle on GLP-1? What the studies show, how protein and training help you keep muscle — and why body composition matters more than the scale.\n\n","1200x600",{"name":171,"created_at":172,"published_at":173,"updated_at":174,"id":175,"uuid":176,"content":177,"slug":190,"full_slug":191,"sort_by_date":192,"position":193,"tag_list":194,"is_startpage":20,"parent_id":195,"meta_data":192,"group_id":196,"first_published_at":197,"release_id":192,"lang":198,"path":192,"alternates":199,"default_full_slug":191,"translated_slugs":208,"_stopResolving":18},"Ion Haab","2025-05-09T09:08:27.040Z","2026-07-13T13:12:15.043Z","2026-07-13T13:12:15.058Z",667188311,"9bce9c6c-da14-4e75-bb28-cc5fa141f16f",{"_uid":178,"name":171,"role":179,"photo":180,"isFemale":20,"linkedin":184,"location":187,"component":188,"description":189},"ba3aab97-7f88-42ae-a0d6-8f3a8f778bbb","Co-Founder & CEO",{"id":181,"alt":121,"name":121,"focus":121,"title":121,"source":121,"filename":182,"copyright":121,"fieldtype":125,"meta_data":183,"is_external_url":20},22188452,"https://a.storyblok.com/f/103647/160x160/0e3f6c1029/image_160.png",{},{"id":121,"url":185,"linktype":186,"fieldtype":166,"cached_url":185},"https://www.linkedin.com/in/ionhaab/?originalSubdomain=ch","url","Zurich, Switzerland","author","Ion is the CEO and Co-Founder of CARE, a digital health company with a vision to shape the future of healthcare through prevention — making it more accessible and understandable for everyone.\n\n\n\n\n\n","ion-haab","ch-en/blog/authors/ion-haab",null,-10,[],417185127,"0fc6c493-f890-42fa-9716-3ec46202c6e5","2025-05-12T06:52:11.455Z","default",[200,204],{"id":201,"name":171,"slug":190,"published":18,"full_slug":202,"is_folder":20,"parent_id":203},667229092,"ch-fr/blog/authors/ion-haab",667229091,{"id":205,"name":171,"slug":190,"published":18,"full_slug":206,"is_folder":20,"parent_id":207},667229075,"ch-de/blog/authors/ion-haab",417185126,[],"blog-detail",[211],{"name":6,"created_at":212,"published_at":213,"updated_at":214,"id":215,"uuid":5,"content":216,"slug":9,"full_slug":7,"sort_by_date":192,"position":219,"tag_list":220,"is_startpage":20,"parent_id":221,"meta_data":192,"group_id":222,"first_published_at":213,"release_id":192,"lang":198,"path":192,"alternates":223,"default_full_slug":7,"translated_slugs":224,"_stopResolving":18},"2026-07-10T08:05:34.345Z","2026-07-10T08:05:53.088Z","2026-07-10T08:05:53.101Z",196530726315543,{"_uid":217,"title":6,"component":218},"eb4823f2-8d98-4589-b527-123b2de64101","category",-50,[],417185122,"471c43a9-de60-4066-85e7-5f03782d645d",[],[],"When you lose weight on GLP-1, you don’t only lose fat — you also lose some muscle. 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If you only watch the scale, you miss the part that matters most: your body composition.\n\n\n","2026-07-06 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