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Check-up","cta-book-check-up-nav",[556],{"alt":112,"src":557,"_uid":561,"component":197},{"id":558,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":559,"copyright":112,"fieldtype":114,"meta_data":560,"is_external_url":20},70267014332781,"https://a.storyblok.com/f/103647/3600x2400/d531c070d6/mobile-menu-image-de.png",{},"1ed001a5-2ea1-4a1d-96ba-b8adcdc149e2",[563],{"_uid":564,"text":565,"hidden":20,"component":566},"84ef1cc5-5080-44dc-9675-7ef35d038650","Get started with our medical weight loss programme: [Check eligibility](https://care.health/ch-en/tests/medical-weight-loss/)","Notification Component",[568,571,574,577,580,583],{"_uid":569,"text":570,"hidden":20,"component":566},"31ed7e1a-d6b4-49a4-92a6-68c9c4e4998d","**🎉 20% discount** on all CARE services in January with **code JAN25**. [Benefit now!](https://booking.care.me/ch-en/services/?coupon=JAN25)",{"_uid":572,"text":573,"hidden":20,"component":566},"bd798bad-151d-4e50-97df-bd75a141b419","🎁 **Health as Christmas gift:** Surprise your loved ones with a **CARE voucher** - [Buy now](/ch-en/gift)",{"_uid":575,"text":576,"hidden":20,"component":566},"8e50790e-14cf-4b2e-a12d-c278b110cb01","🎁 Get **CHF 50.– off** your Check-up until 30/09! Apply the code **CHECK50** at checkout.",{"_uid":578,"text":579,"hidden":20,"component":566},"18e9568a-b21a-46e0-a1dc-09452b872bda","☀️ **Only this month:** Save 20% on all tests with code **SUMMER20** – [Book now!](https://booking.care.me/ch-en/services/?coupon=SUMMER20)",{"_uid":581,"text":582,"type":112,"hidden":20,"component":566},"3ac1857a-44e6-48c7-bdfe-e26796bf631b","**Celebrating 3 Years of CARE 🎉** Get 20% discount on all services with **code HBD20**. [Book now!](https://booking.care.me/ch-en/locations/?coupon=HBD20)",{"_uid":584,"text":585,"hidden":20,"component":566},"d471a12c-ac93-456e-9583-92fbe8368a45","⚡️Black Weekend: **25% off** all services with code **BLK25** – only until Sunday night! [Book now!](https://booking.care.me/ch-en/services/?coupon=BLK25)","page-settings","🍪 Diese Website verwendet Cookies um die Funktionalität unserer Website sicherzustellen und das Benutzererlebnis zu verbessern, sowie zu Analyse- und zu Marketingzwecken. [Mehr erfahren](/de/cookie-richtlinien/)","ch-en/config/page-settings",0,[],417185108,"ed5c1cc0-8ffc-49e1-992d-4c6e88d8962f","2023-08-18T09:11:06.612Z",[595,599,603,607],{"id":596,"name":169,"slug":586,"published":20,"full_slug":597,"is_folder":20,"parent_id":598},359960885,"archive/config/page-settings",359960846,{"id":600,"name":169,"slug":586,"published":20,"full_slug":601,"is_folder":20,"parent_id":602},417185182,"archive/us-en/config/page-settings",417185105,{"id":604,"name":169,"slug":586,"published":18,"full_slug":605,"is_folder":20,"parent_id":606},641884433,"ch-fr/config/page-settings",641884251,{"id":608,"name":169,"slug":586,"published":18,"full_slug":609,"is_folder":20,"parent_id":610},417185181,"ch-de/config/page-settings",417185107,[],[],[614,615,616,617,618,619,620,621,622,623,624,625,626,627,628,629,630,631],{"name":414,"id":415,"uuid":411,"slug":416,"url":417,"full_slug":417},{"name":254,"id":255,"uuid":251,"slug":256,"url":252,"full_slug":252},{"name":380,"id":381,"uuid":377,"slug":382,"url":378,"full_slug":378},{"name":284,"id":285,"uuid":281,"slug":286,"url":282,"full_slug":282},{"name":533,"id":534,"uuid":530,"slug":535,"url":531,"full_slug":531},{"name":265,"id":266,"uuid":262,"slug":267,"url":263,"full_slug":263},{"name":425,"id":426,"uuid":422,"slug":427,"url":423,"full_slug":423},{"name":350,"id":351,"uuid":347,"slug":352,"url":348,"full_slug":348},{"name":336,"id":337,"uuid":333,"slug":338,"url":334,"full_slug":334},{"name":360,"id":361,"uuid":357,"slug":362,"url":358,"full_slug":358},{"name":293,"id":294,"uuid":290,"slug":295,"url":291,"full_slug":291},{"name":370,"id":371,"uuid":367,"slug":372,"url":368,"full_slug":368},{"name":274,"id":275,"uuid":271,"slug":276,"url":272,"full_slug":272},{"name":395,"id":396,"uuid":392,"slug":397,"url":393,"full_slug":393},{"name":434,"id":435,"uuid":431,"slug":436,"url":432,"full_slug":432},{"name":313,"id":314,"uuid":310,"slug":315,"url":311,"full_slug":311},{"name":405,"id":406,"uuid":402,"slug":407,"url":403,"full_slug":403},{"name":91,"id":323,"uuid":320,"slug":324,"url":321,"full_slug":321},{"cache-control":145,"connection":146,"content-encoding":147,"content-type":148,"date":633,"etag":634,"referrer-policy":151,"sb-be-version":635,"server":153,"transfer-encoding":154,"vary":155,"via":636,"x-amz-cf-id":637,"x-amz-cf-pop":158,"x-cache":159,"x-content-type-options":160,"x-frame-options":161,"x-permitted-cross-domain-policies":162,"x-request-id":638,"x-runtime":639,"x-xss-protection":165},"Tue, 25 Aug 2026 13:54:50 GMT","W/\"402d9d719f7fe906058f44a71a7c9b45\"","5.946.1","1.1 4f35d614834a657989bbb3f4ece2854a.cloudfront.net (CloudFront)","2qE1NWN7CB2VFi4ruR0etXQo8RaFX7gVluEOEWJdZXJPo1mMUj6vDw==","eba12458-24a5-4106-b003-714385c6010a","0.056800",[641,786,878,974,1083],{"name":642,"created_at":643,"published_at":644,"updated_at":645,"id":646,"uuid":647,"content":648,"slug":765,"full_slug":766,"sort_by_date":124,"position":767,"tag_list":768,"is_startpage":20,"parent_id":769,"meta_data":124,"group_id":770,"first_published_at":771,"release_id":124,"lang":130,"path":124,"alternates":772,"default_full_slug":766,"translated_slugs":785},"Your Baseline: The Health Markers Worth Knowing Before a Weight-Loss Programme","2026-08-04T11:31:11.171Z","2026-08-18T19:48:44.351Z","2026-08-18T19:48:44.367Z",205428617948165,"7a3152c5-a68f-4f20-8158-b28a92387877",{"_uid":649,"body":650,"meta":693,"title":642,"author":700,"reviewer":731,"component":741,"categories":742,"description":757,"publishedAt":758,"heroMobileImage":759,"heroDesktopImage":763},"b97db241-575c-4bc4-b8bd-f4744e6d060b",[651,655,658,670,673,682,685,690],{"_uid":652,"content":653,"component":654},"c23b2881-33ba-451d-94ea-fe11b463d464","# The 3 key takeaways\n\n- **A successful weight loss treatment starts with a health baseline—not with medication.** Understanding where you stand is the foundation of effective care.\n- **Many people have undiagnosed metabolic conditions.** A comprehensive baseline assessment can detect them early.\n- Knowing your health markers improves **safety,** enables **personalised** treatment and makes **progress measurable.**\n\nImagine planning a long journey without knowing your starting point. That’s what beginning a weight loss treatment is like if you don’t know where your body stands today.\n\nA **baseline assessment**—a health check at the beginning of your journey—provides exactly that information. It’s not just an administrative step, but the foundation for treatment that is safe, personalised and measurable. This article explains which health markers matter most—and why.\n\n## Why establish a baseline before starting weight loss treatment?\n\nThere are three practical reasons:\n\n### \n\n**Safety.** Some health markers determine **whether and how treatment should be managed**, including liver function, kidney function and thyroid health. Because weight loss treatment can affect these systems, it’s important to document your baseline values before you begin.\n\n**Personalisation**. Two people with the same body weight can have completely different metabolic profiles. Only by understanding your individual health markers can treatment be tailored specifically to you.\n\n**Measuring progress and staying motivated.** When you know your starting point, you can measure meaningful progress—not only in kilograms lost, but also through improvements in **blood sugar, blood lipids, liver health and body composition**.\n\nThere’s another important point that’s often overlooked: **many metabolic conditions remain symptom-free for years**. A considerable proportion of seemingly healthy adults unknowingly live with **insulin resistance, prediabetes or fatty liver disease**.\n\nFatty liver disease is particularly common in people with impaired glucose metabolism. Around **70% of people with type 2 diabetes** are affected (American Diabetes Association Consensus Report, *Diabetes Care*, 2025), and the condition is strongly associated with excess body weight (Younossi et al., *Hepatology*, 2016) \\[3\\]\\[2\\].\n\nA baseline assessment makes these conditions visible—while there is still time to take effective action.\n\n## Which health markers matter—and why?\n\nThe [**Weight Loss Check-up**](/ch-en/tests/medical-weight-loss) focuses on the health markers that are most important for **metabolic health, cardiovascular risk and safe weight loss treatment**.\n\nThe key areas include:\n\n- **Glucose metabolism and insulin:** helps identify insulin resistance or prediabetes early—often before symptoms appear.\n- **Blood lipids** (such as cholesterol, LDL cholesterol and triglycerides): provide insight into cardiovascular risk, which is closely linked to excess weight.\n- **Blood pressure:** commonly elevated in people with overweight or obesity and a major cardiovascular risk factor.\n- **Liver health:** excess weight is often associated with fatty liver disease—a common condition that can often be improved.\n- **Kidney function:** important for identifying early vascular changes and monitoring overall health.\n- **Inflammatory markers:** may provide insight into chronic low-grade inflammation associated with metabolic disease.\n- **Body composition (muscle and fat analysis):** provides a more detailed understanding of your body composition (see the next section).\n\nThese are the key areas covered by the **Weight Loss Check-up**. If you’re looking for a more comprehensive assessment—including your **thyroid function, vitamin levels or iron status**—the [**Full Body Check-up**](/ch-en/full-body-check-up) offers a broader evaluation.","blog-detail-markdown",{"_uid":656,"content":657,"component":654},"f52f4349-6b8c-4d62-937b-c00e2a8de7f5","## Body composition\n\nA kilogram isn’t always just a kilogram. The number on the scale doesn’t tell you whether you’re losing fat or muscle—and that’s exactly what matters during weight loss. A **body composition analysis** shows your body composition: how much fat and how much muscle you have.\n\nAs a baseline, this is valuable because it allows you to measure your progress later on. We explain why this is so important in our article on **muscle and body composition**.\n\n## Why your baseline matters most for your safety\n\nA baseline assessment isn’t just “nice to have.” It helps identify contraindications early (there are situations in which medical weight loss treatment is not recommended) and allows your treatment to be managed safely and tailored to your individual needs.\n\nWhen it comes to costs: In Switzerland, medication for weight loss is covered by mandatory basic health insurance only under strict conditions and through specialist physicians. The **CARE** [**Weight Loss Programme**](/ch-en/tests/medical-weight-loss) is independent of this process and is a **self-pay service**. It is currently **not covered by health insurance**.\n\nThe baseline assessment is therefore primarily about **your safety and ensuring an individually tailored treatment**, not about qualifying for reimbursement.",{"_uid":659,"imageFit":660,"imageNew":661,"component":662,"description":112,"mobileImage":663,"desktopImage":668},"70ec09ce-7f83-4dcf-84d9-8fcfafc17df3","cover",[],"blog-detail-image-with-description",{"id":664,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":665,"copyright":112,"fieldtype":114,"meta_data":666,"is_external_url":20},205750266438856,"https://a.storyblok.com/f/103647/2400x1800/555902dc8d/baseline_check.png",{"size":667},"2400x1800",{"id":664,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":665,"copyright":112,"fieldtype":114,"meta_data":669,"is_external_url":20},{"size":667},{"_uid":671,"content":672,"component":654},"91a7e26a-5b28-4ced-93bf-a8d945de852a","### How CARE establishes your baseline: the Weight Loss Check-up\n\nAt **CARE**, your journey begins with a short **eligibility assessment**. If a medically supervised weight loss programme is right for you, the [**Weight Loss Check-up**](/ch-en/tests/medical-weight-loss) serves as your baseline assessment and is the minimum requirement before starting treatment—designed to be simple and straightforward.\n\n- **Blood test, muscle and fat analysis, and blood pressure measurement** in one appointment—covering **102 biomarkers**, with a focus on cardiovascular and metabolic risk factors.\n- **Performed at a partner laboratory in Switzerland**, usually in less than **20 minutes**—no doctor’s appointment required.\n- **Physician-reviewed results** delivered in the app, presented in an easy-to-understand format with clear recommendations (usually within **10–15 days**).\n- **Monthly follow-up measurements** so your progress can be tracked over time.\n\nThe **Weight Loss Check-up** covers the key areas discussed in this article: **blood lipids, glucose metabolism and insulin resistance, liver function, kidney function, inflammation, blood pressure and body composition**. Additional markers (such as **thyroid function** or **vitamin levels**) can be added if needed.\n\nA note on costs: If the **Weight Loss Check-up** is the starting point for a weight loss treatment programme, it is a **self-pay service**. In this case, supplementary health insurance will generally not reimburse the cost, as the questionnaire has already identified risk factors that the check-up is intended to confirm. (A purely preventive check-up, without any known risk factors, may be reimbursed depending on your supplementary insurance.)\n\n**Take the first step: check your eligibility.** Entry into a medically supervised weight loss programme begins with a short eligibility assessment. If you’re eligible, the **Weight Loss Check-up**—your baseline assessment—is the next step. No obligation, physician-reviewed and no pressure.\n\n**→** [**Check your eligibility**](/ch-en/tests/medical-weight-loss)",{"_uid":674,"imageFit":660,"imageNew":675,"component":662,"description":112,"mobileImage":676,"desktopImage":680},"744607da-9ba7-4532-becc-1d28a64b9a59",[],{"id":677,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":678,"copyright":112,"fieldtype":114,"meta_data":679,"is_external_url":20},205750266369222,"https://a.storyblok.com/f/103647/2400x1800/97d210c34a/eligibility_check_en.png",{"size":667},{"id":677,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":678,"copyright":112,"fieldtype":114,"meta_data":681,"is_external_url":20},{"size":667},{"_uid":683,"content":684,"component":654},"455c07fb-5a9e-450f-b242-53169e59e0fc","## **In brief**\n\nWeight loss treatment doesn’t begin with medication—it begins with understanding where you stand. A baseline assessment, including blood tests, blood pressure and body composition, makes treatment more personalised and goal-oriented while identifying previously undetected metabolic conditions at an early stage, when they can still be addressed effectively. **First the baseline, then the plan.**\n\n## Frequently asked questions\n\n**Which health markers should be checked before starting weight loss treatment?** Typically, these include **glucose metabolism** (fasting glucose and HbA1c), **blood lipids**, **blood pressure**, **liver and kidney function**, **thyroid function**, as well as **iron and vitamin levels**, complemented by a **body composition analysis**. Your physician will determine which tests are appropriate for your individual situation.\n\n**Why isn’t the scale enough?** The scale only shows your **total body weight**. It doesn’t tell you anything about your **body composition** or your **metabolic risk factors**—both of which are more important for safe and successful treatment.\n\n**How long does a baseline assessment at CARE take?** The **Weight Loss Check-up** at a CARE partner laboratory usually takes **less than 20 minutes** and includes a blood test, body composition analysis, blood pressure measurement and the assessment of **102 biomarkers**. Your results are then reviewed by a physician and are available in the app within approximately **10–15 days**.\n\n**Do I have to start treatment afterwards?** No. A baseline assessment is designed to give you clarity first. What you decide to do next is something you discuss together with your physician.",{"_uid":686,"title":687,"content":688,"component":689},"c36bc18b-1cdf-468a-a844-f2241f9068fd","List of References","\\[1\\] Apovian CM, Aronne LJ, Bessesen DH, et al. *Pharmacological Management of Obesity: An Endocrine Society Clinical Practice Guideline.* J Clin Endocrinol Metab. 2015;100(2):342–362. (Co-sponsors: European Society of Endocrinology, The Obesity Society; GRADE-based.) [PMID 25590212](https://pubmed.ncbi.nlm.nih.gov/25590212/).\n\n\\[2\\] Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. *Global epidemiology of nonalcoholic fatty liver disease — Meta-analytic assessment of prevalence, incidence, and outcomes.* Hepatology. 2016;64(1):73–84. doi:[10.1002/hep.28431](https://doi.org/10.1002/hep.28431). [PMID 26707365](https://pubmed.ncbi.nlm.nih.gov/26707365/).\n\n\\[3\\] American Diabetes Association. *Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report.* Diabetes Care. 2025;48(7):1057. \u003Chttps://diabetesjournals.org/care/article/48/7/1057/160536/Metabolic-Dysfunction-Associated-Steatotic-Liver> (online 28 May 2025).","BlogDetailCollapsibleMarkdown",{"_uid":691,"content":692,"component":654},"65ea0c41-1796-43fd-8355-ba260ca642a9","### **Medical disclaimer**\n\n*This article is for general information and health education. It does not replace individual medical advice, diagnosis or treatment. Which examinations make sense for you is decided in a medical assessment. If you have health concerns, please consult a doctor.*",[694],{"_uid":695,"title":696,"no_index":20,"og_image":697,"canonical":698,"component":235,"no_follow":20,"description":699,"image_param":237,"hide_sitemap":20},"95269a16-d9b8-47b3-9cf0-6b89f0c1a6bb","Health Check Before Weight Loss: Your Baseline","//a.storyblok.com/f/103647/2400x1200/6c0cf8ac49/meta-image.png",{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},"Before you start a weight-loss programme: which blood and body markers to know, and why your baseline shapes safety and results — explained by doctors.\n\n\n",{"name":701,"created_at":702,"published_at":703,"updated_at":704,"id":705,"uuid":706,"content":707,"slug":717,"full_slug":718,"sort_by_date":124,"position":719,"tag_list":720,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":721,"first_published_at":722,"release_id":124,"lang":130,"path":124,"alternates":723,"default_full_slug":718,"translated_slugs":730,"_stopResolving":18},"Ion Haab","2025-05-09T09:08:27.040Z","2026-08-18T09:10:23.353Z","2026-08-18T09:10:23.368Z",667188311,"9bce9c6c-da14-4e75-bb28-cc5fa141f16f",{"_uid":708,"name":701,"role":709,"photo":710,"isFemale":20,"linkedin":714,"location":119,"component":120,"description":716},"ba3aab97-7f88-42ae-a0d6-8f3a8f778bbb","Co-Founder & CEO",{"id":711,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":712,"copyright":112,"fieldtype":114,"meta_data":713,"is_external_url":20},91421379629658,"https://a.storyblok.com/f/103647/3000x2000/85c54e313b/img-rectangle-ion-haab.png",{},{"id":112,"url":715,"linktype":186,"fieldtype":118,"cached_url":715},"https://www.linkedin.com/in/ionhaab/?originalSubdomain=ch","Ion co-founded CARE in 2022 with the vision of making preventive healthcare accessible, understandable, and digital for everyone. Under his leadership, CARE has grown from a doctor’s practice into a platform model for modern prevention. He holds a Master’s degree in Business Innovation from the University of St. Gallen (HSG) and has experience as a strategy consultant. With CARE, his ambition is to create real value for people and society.\n\n\n\n\n","ion-haab","ch-en/blog/authors/ion-haab",-10,[],"0fc6c493-f890-42fa-9716-3ec46202c6e5","2025-05-12T06:52:11.455Z",[724,727],{"id":725,"name":701,"slug":717,"published":18,"full_slug":726,"is_folder":20,"parent_id":135},667229075,"ch-de/blog/authors/ion-haab",{"id":728,"name":701,"slug":717,"published":18,"full_slug":729,"is_folder":20,"parent_id":139},667229092,"ch-fr/blog/authors/ion-haab",[],{"name":100,"created_at":101,"published_at":102,"updated_at":103,"id":104,"uuid":105,"content":732,"slug":122,"full_slug":123,"sort_by_date":124,"position":125,"tag_list":736,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":128,"first_published_at":129,"release_id":124,"lang":130,"path":124,"alternates":737,"default_full_slug":123,"translated_slugs":740,"_stopResolving":18},{"_uid":107,"name":108,"role":109,"photo":733,"isFemale":18,"linkedin":735,"location":119,"component":120,"description":121},{"id":111,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":113,"copyright":112,"fieldtype":114,"meta_data":734,"is_external_url":20},{},{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},[],[738,739],{"id":133,"name":100,"slug":122,"published":18,"full_slug":134,"is_folder":20,"parent_id":135},{"id":137,"name":100,"slug":122,"published":18,"full_slug":138,"is_folder":20,"parent_id":139},[],"blog-detail",[743],{"name":6,"created_at":744,"published_at":745,"updated_at":746,"id":747,"uuid":5,"content":748,"slug":9,"full_slug":7,"sort_by_date":124,"position":751,"tag_list":752,"is_startpage":20,"parent_id":753,"meta_data":124,"group_id":754,"first_published_at":745,"release_id":124,"lang":130,"path":124,"alternates":755,"default_full_slug":7,"translated_slugs":756,"_stopResolving":18},"2026-07-10T08:05:34.345Z","2026-07-10T08:05:53.088Z","2026-07-10T08:05:53.101Z",196530726315543,{"_uid":749,"title":6,"component":750},"eb4823f2-8d98-4589-b527-123b2de64101","category",-50,[],417185122,"471c43a9-de60-4066-85e7-5f03782d645d",[],[],"Before you change your body, it helps to know where it stands. A proper baseline — blood markers, blood pressure and body composition — makes a weight-loss programme safer, more personal and easier to measure. It often surfaces things you had no idea about (such as pre-diabetes or a fatty liver), and it’s the foundation for a programme that’s medically well run from day one.\n\n","2026-08-05 09:00",{"id":760,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":761,"copyright":112,"fieldtype":114,"meta_data":762,"is_external_url":20},205750266574025,"https://a.storyblok.com/f/103647/2400x1800/51eef61f68/hero-4.png",{"size":667},{"id":760,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":761,"copyright":112,"fieldtype":114,"meta_data":764,"is_external_url":20},{},"health-check-before-weight-loss","ch-en/blog/articles/health-check-before-weight-loss",-830,[],417185118,"a92fd071-a2d6-450a-a0e5-862bf2f43ffc","2026-08-06T10:22:16.511Z",[773,779],{"id":774,"name":775,"slug":776,"published":18,"full_slug":777,"is_folder":20,"parent_id":778},205751936972407,"Standortbestimmung: Welche Gesundheitswerte du vor einer Gewichtsbehandlung kennen solltest","standortbestimmung-gesundheitswerte-vor-gewichtsbehandlung","ch-de/blog/articles/standortbestimmung-gesundheitswerte-vor-gewichtsbehandlung",417185117,{"id":780,"name":781,"slug":782,"published":18,"full_slug":783,"is_folder":20,"parent_id":784},205754874597282,"Votre point de départ : les valeurs de santé à connaître avant un traitement minceur","bilan-initial-avant-un-traitement-de-perte-de-poids","ch-fr/blog/articles/bilan-initial-avant-un-traitement-de-perte-de-poids",196538689504798,[],{"name":787,"created_at":788,"published_at":789,"updated_at":790,"id":791,"uuid":792,"content":793,"slug":860,"full_slug":861,"sort_by_date":124,"position":862,"tag_list":863,"is_startpage":20,"parent_id":769,"meta_data":124,"group_id":864,"first_published_at":865,"release_id":124,"lang":130,"path":124,"alternates":866,"default_full_slug":861,"translated_slugs":877},"Understanding Body Composition: How to Read Muscle Mass, Body Fat & Visceral Fat","2026-08-05T10:26:38.154Z","2026-08-18T19:48:35.570Z","2026-08-18T19:48:35.585Z",205766648474460,"8efe68e3-aa67-412f-b5e4-02d062c18038",{"_uid":649,"body":794,"meta":821,"title":787,"author":826,"reviewer":836,"component":741,"categories":846,"description":852,"publishedAt":853,"heroMobileImage":854,"heroDesktopImage":858},[795,797,805,807,815,817,819],{"_uid":652,"content":796,"component":654},"## The most important points in 3 takeaways\n\n- Two people with the same body weight can have completely different **body compositions**.\n- **Visceral fat** is the metabolically active fat surrounding your organs and is closely linked to cardiovascular risk.\n- **Muscle mass** supports your metabolic capacity – low muscle mass has been associated with higher mortality in scientific studies.\n\nThis article explains the most important body composition metrics, what they mean for your health, and how to interpret them – no degree in statistics required.\n\n## What is body composition?\n\nYour body is made up – broadly speaking – of **fat, muscle, water, and bone**. Body composition describes how your body weight is distributed across these different components.\n\nThis explains a common observation: Two people who are the same height and weigh exactly the same can look completely different – and have very different health profiles. One may have more muscle, the other more body fat. On the scale, they are identical. Beneath the surface, they are not.\n\n## Why body composition tells you more than the scale – and BMI\n\nBody weight and BMI do not distinguish between fat and muscle, nor do they tell you **where** fat is stored. Yet this is exactly what matters:\n\n**Where fat is stored:** Fat surrounding the organs (visceral fat) is metabolically active and poses a greater health risk than subcutaneous fat.\n\n**How much muscle you have:** Muscle is your body's metabolic engine. It supports metabolic health, strength, and physical function – especially as you age.\n\nThat is why body composition provides a more accurate picture of your health than a single number on the scale.\n\n## The most important metrics – and how to interpret them\n\n### Skeletal muscle mass\n\nMuscles use energy, help regulate blood sugar, and support metabolic flexibility. Low muscle mass is not simply a matter of appearance: A meta-analysis of 16 studies involving more than 81,000 participants found that low skeletal muscle mass was associated with an approximately **57% higher risk** of all-cause mortality (PLOS One, 2023). More muscle is therefore an important part of preventive health.\n\n### Body fat percentage\n\nBody fat percentage shows how much of your body weight consists of fat. It is more informative than BMI because it distinguishes fat from muscle. Interpretation should always take **sex, age, and the measurement method** into account. In most cases, **changes over time** are more meaningful than a single measurement.\n\n### Visceral fat\n\nVisceral fat is the fat stored **around your internal organs**. It is metabolically active tissue that releases free fatty acids and inflammatory signalling molecules, contributing to metabolic dysfunction. Systematic reviews have associated higher levels of visceral fat with a less favourable cardiometabolic profile and increased mortality (Frontiers in Endocrinology, 2022).\n\n## Reading the muscle-fat analysis: understanding the bar chart\n\nMany body composition analyses display three bars stacked vertically: **body weight, skeletal muscle mass, and body fat mass**. A simple rule of thumb is that a **longer muscle bar** than fat bar (with both remaining proportional to your overall weight) is generally a positive sign. A shorter muscle bar combined with a longer fat bar suggests there may be room for improvement. The most important aspect is the **overall pattern** – and how it changes over time.",{"_uid":659,"imageFit":660,"imageNew":798,"component":662,"description":112,"mobileImage":799,"desktopImage":803},[],{"id":800,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":801,"copyright":112,"fieldtype":114,"meta_data":802,"is_external_url":20},205768940191474,"https://a.storyblok.com/f/103647/2400x1800/d9d73067ab/more_than_the_scale_en.png",{"size":667},{"id":800,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":801,"copyright":112,"fieldtype":114,"meta_data":804,"is_external_url":20},{"size":667},{"_uid":671,"content":806,"component":654},"## What are “good” values?\n\nThere is no single ideal number. Healthy ranges vary depending on age, sex, fitness level, and the measurement method used. Two principles are more helpful than any reference table:\n\n**Trends matter more than single measurements.** If your body fat is decreasing while your muscle mass stays stable or increases, you’re moving in the right direction—regardless of where you started.\n\n**Balance matters more than individual numbers.** The ratio of muscle to fat (combined with low visceral fat) is more meaningful than any single percentage.\n\nThe best way to understand what **your** specific results mean is to discuss them with a healthcare professional.\n\n## What you can do\n\nThe two most effective strategies are:\n\n**Strength training** builds and preserves muscle mass (aim for 2–3 sessions per week for meaningful results).\n\n**Getting enough protein** helps preserve muscle, especially during weight loss.\n\n**Zone 2 exercise** (60–70% of your maximum heart rate) is one of the most effective ways to reduce visceral fat.\n\nIf you’re trying to lose weight, preserving muscle mass is essential. We explain why in detail in our article on [muscle and weight loss](/ch-en/blog/articles/muscle-not-just-kilos-why-body-composition-matters-when-you-lose-weight-on-glp-1).\n\n## Why trends matter more than a single measurement\n\nA single measurement is like a photograph. What you really want is the **movie**: Is your body composition moving in the right direction?\n\nThat’s why CARE doesn’t measure body composition just once. As part of your treatment, it is measured **monthly**. This allows you to see whether you’re losing fat while maintaining muscle mass—and adjust your plan accordingly.\n\n## What a CARE body composition analysis measures\n\nA CARE body composition analysis measures far more than your weight and body fat percentage. In just a few minutes, it provides a comprehensive overview across four key areas:\n\n**Body Score** – an overall score (0–100) that combines your measurements into a single assessment and helps you track your progress over time.\n\n**Muscle & Metabolism** – Skeletal Muscle Index (SMI), Fat-Free Mass Index (FFMI), and **Basal Metabolic Rate** (BMR): showing how much energy your body burns at rest.\n\n**Muscle & Fat Mass** – your body weight, skeletal muscle mass, and body fat mass in kilograms.\n\n**Fat Analysis** – body fat percentage, BMI, **waist-to-height ratio**, **waist circumference**, and **visceral fat**—the metabolically active fat surrounding your organs.\n\nThis allows you to see not only whether things are changing, but exactly what is changing—muscle, fat, metabolism, and visceral fat are all assessed separately. Your results are then interpreted by a physician to create a personalised plan, rather than leaving you with a collection of numbers.\n\nKnow your numbers. A muscle and fat analysis is part of the CARE **Full Body Check-up**, together with blood tests and blood pressure measurements—all reviewed by a physician. That way, you’ll know where you stand instead of guessing.\n\n**→ Discover the CARE** [**Full Body Check-up**](/ch-en/full-body-check-up)\n\n**Already receiving treatment with CARE?** Your monthly muscle and fat analysis, along with your progress over time, is available in the App.",{"_uid":674,"imageFit":660,"imageNew":808,"component":662,"description":112,"mobileImage":809,"desktopImage":813},[],{"id":810,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":811,"copyright":112,"fieldtype":114,"meta_data":812,"is_external_url":20},205768940367605,"https://a.storyblok.com/f/103647/2400x1800/1a6e6a3c63/what_care_shows_en.png",{"size":667},{"id":810,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":811,"copyright":112,"fieldtype":114,"meta_data":814,"is_external_url":20},{"size":667},{"_uid":683,"content":816,"component":654},"## **In brief**\n\nYour body composition tells you far more about your health than your weight or BMI. It shows how much muscle supports your body, how much body fat you have, and how much of that fat is stored as visceral fat around your organs. Focus less on individual numbers and more on the overall balance and how your results change over time. And remember the two habits that make the biggest difference: strength training and getting enough protein.\n\n## Frequently asked questions\n\n**What is the difference between body fat percentage and BMI?** BMI simply compares your weight to your height and does not distinguish between fat and muscle. Body fat percentage shows directly how much of your body weight is made up of fat, making it a more informative measure.\n\n**Why is visceral fat more dangerous than other types of fat?** Because it is metabolically active. It releases free fatty acids and inflammatory signalling molecules and is associated with a higher risk of cardiovascular and metabolic disease.\n\n**What is a healthy body fat percentage?** That depends on your sex, age, and the measurement method used. There is no single “healthy” number. The trend over time and the balance between muscle and fat are far more meaningful. Your results are best interpreted by a healthcare professional.\n\n**How often should you measure your body composition?** A single measurement provides only limited information—the trend over time is what matters. As part of an ongoing treatment plan, measuring body composition once a month is a practical way to track your progress.",{"_uid":686,"title":687,"content":818,"component":689},"\\[1\\] *Low skeletal muscle mass index and all-cause mortality risk in adults: a systematic review and meta-analysis of prospective cohort studies.* PLOS One. 2023. doi:[10.1371/journal.pone.0286745](https://doi.org/10.1371/journal.pone.0286745). (16 prospective cohorts, >81,000; pooled RR 1.57)\n\n*\\[2\\] Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review.* Front Endocrinol (Lausanne). 2022. doi:[10.3389/fendo.2022.922931](https://doi.org/10.3389/fendo.2022.922931) ([PMC9446237](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446237/)).",{"_uid":691,"content":820,"component":654},"### **Medical disclaimer**\n\nThis article is intended for general information and health education only. It does not replace personalised medical advice, diagnosis, or treatment. The meaning of your individual results should always be interpreted by a qualified healthcare professional. If you have any health concerns or symptoms, please consult a doctor.",[822],{"_uid":695,"title":823,"no_index":20,"og_image":697,"canonical":824,"component":235,"no_follow":20,"description":825,"image_param":237,"hide_sitemap":20},"Understanding Body Composition: Muscle, Fat & Visceral",{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},"What muscle mass, body fat percentage and visceral fat really say about your health — and how to read your muscle-fat analysis. Explained by doctors.\n\n\n\n",{"name":701,"created_at":702,"published_at":703,"updated_at":704,"id":705,"uuid":706,"content":827,"slug":717,"full_slug":718,"sort_by_date":124,"position":719,"tag_list":831,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":721,"first_published_at":722,"release_id":124,"lang":130,"path":124,"alternates":832,"default_full_slug":718,"translated_slugs":835,"_stopResolving":18},{"_uid":708,"name":701,"role":709,"photo":828,"isFemale":20,"linkedin":830,"location":119,"component":120,"description":716},{"id":711,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":712,"copyright":112,"fieldtype":114,"meta_data":829,"is_external_url":20},{},{"id":112,"url":715,"linktype":186,"fieldtype":118,"cached_url":715},[],[833,834],{"id":725,"name":701,"slug":717,"published":18,"full_slug":726,"is_folder":20,"parent_id":135},{"id":728,"name":701,"slug":717,"published":18,"full_slug":729,"is_folder":20,"parent_id":139},[],{"name":100,"created_at":101,"published_at":102,"updated_at":103,"id":104,"uuid":105,"content":837,"slug":122,"full_slug":123,"sort_by_date":124,"position":125,"tag_list":841,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":128,"first_published_at":129,"release_id":124,"lang":130,"path":124,"alternates":842,"default_full_slug":123,"translated_slugs":845,"_stopResolving":18},{"_uid":107,"name":108,"role":109,"photo":838,"isFemale":18,"linkedin":840,"location":119,"component":120,"description":121},{"id":111,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":113,"copyright":112,"fieldtype":114,"meta_data":839,"is_external_url":20},{},{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},[],[843,844],{"id":133,"name":100,"slug":122,"published":18,"full_slug":134,"is_folder":20,"parent_id":135},{"id":137,"name":100,"slug":122,"published":18,"full_slug":138,"is_folder":20,"parent_id":139},[],[847],{"name":6,"created_at":744,"published_at":745,"updated_at":746,"id":747,"uuid":5,"content":848,"slug":9,"full_slug":7,"sort_by_date":124,"position":751,"tag_list":849,"is_startpage":20,"parent_id":753,"meta_data":124,"group_id":754,"first_published_at":745,"release_id":124,"lang":130,"path":124,"alternates":850,"default_full_slug":7,"translated_slugs":851,"_stopResolving":18},{"_uid":749,"title":6,"component":750},[],[],[],"Your weight is just a single number – your body composition shows how much muscle mass and body fat you have, and where that fat is stored. In particular, visceral fat (the fat surrounding your organs) and your muscle mass tell you more about your health than your body weight or your BMI.\n","2026-08-03 09:00",{"id":855,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":856,"copyright":112,"fieldtype":114,"meta_data":857,"is_external_url":20},205768940392182,"https://a.storyblok.com/f/103647/2400x1800/24f48fe0bc/hero-en.png",{"size":667},{"id":855,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":856,"copyright":112,"fieldtype":114,"meta_data":859,"is_external_url":20},{"size":667},"understanding-body-composition-muscle-mass-body-fat-visceral-fat","ch-en/blog/articles/understanding-body-composition-muscle-mass-body-fat-visceral-fat",-820,[],"23f33756-bade-42fa-a6bf-07d61f86a94d","2026-08-06T10:22:22.150Z",[867,872],{"id":868,"name":869,"slug":870,"published":18,"full_slug":871,"is_folder":20,"parent_id":778},205766811806774,"Körperzusammensetzung verstehen: Muskel, Fett & Viszeralfett","koerperzusammensetzung-verstehen-muskelmasse-koerperfett-viszeralfett","ch-de/blog/articles/koerperzusammensetzung-verstehen-muskelmasse-koerperfett-viszeralfett",{"id":873,"name":874,"slug":875,"published":18,"full_slug":876,"is_folder":20,"parent_id":784},205779642841266,"Comprendre la composition corporelle : masse musculaire, graisse et graisse viscérale","comprendre-la-composition-corporelle-masse-musculaire-graisse-et-graisse-viscerale","ch-fr/blog/articles/comprendre-la-composition-corporelle-masse-musculaire-graisse-et-graisse-viscerale",[],{"name":879,"created_at":880,"published_at":881,"updated_at":882,"id":883,"uuid":884,"content":885,"slug":956,"full_slug":957,"sort_by_date":124,"position":958,"tag_list":959,"is_startpage":20,"parent_id":769,"meta_data":124,"group_id":960,"first_published_at":961,"release_id":124,"lang":130,"path":124,"alternates":962,"default_full_slug":957,"translated_slugs":973},"GLP-1 Side Effects: What’s Common, What’s Rare – and How to Get Them Under Control","2026-07-28T06:31:55.807Z","2026-08-18T19:48:17.630Z","2026-08-18T19:48:17.647Z",202877811993194,"c207e4de-8b09-4e67-88da-1a8d7701c075",{"_uid":649,"body":886,"meta":917,"title":879,"author":922,"reviewer":932,"component":741,"categories":942,"description":948,"publishedAt":949,"heroMobileImage":950,"heroDesktopImage":954},[887,889,899,901,911,913,915],{"_uid":652,"content":888,"component":654},"## **The 3 key points**\n\n- Most side effects are **gastrointestinal symptoms** (nausea, constipation, diarrhoea), usually mild to moderate and temporary.\n- Tolerance can be improved through **gradual dose increases** — together with appropriate nutrition and fluid intake.\n- Rare but serious side effects can be recognised by clear **warning signs** — in these cases, seek medical advice rather than waiting.\n\nSide effects are one of the most common reasons people do not start treatment at all — or stop it too early. That is understandable. This article explains what is truly common, what is rare, what you can do yourself to manage side effects, and when you should contact a doctor.\n\nNo effective medication is completely free of side effects. The question is not *whether* they occur, but *how likely they are, how severe they are* — and *how well they can be managed*.\n\n## **Which side effects are common?**\n\nBy far the most common side effects are **gastrointestinal symptoms**:\n\n- **Nausea** (the most common of all),\n- vomiting,\n- diarrhoea,\n- constipation,\n- as well as bloating, abdominal pain or feeling full quickly.\n\nThe exact frequency depends on the medication and dose: nausea is reported by around **15 to 44%** of patients, depending on the product and dosage, with higher rates generally seen at the higher doses used for weight management. These symptoms are usually **mild to moderate**, **dose-dependent**, and typically improve within **4 to 8 weeks** as the body adapts.\n\n## **Why does the weight come back? Is it my fault?**\n\nNo. Regain is **not a sign of weakness or a lack of discipline**. Obesity is a recognised **chronic disease**. **GLP-1 medications** treat obesity for as long as they are used, but **they do not cure the disease**. After stopping treatment, hunger, the persistent thoughts about food (“**food noise**”), and the body’s biological counter-regulatory mechanisms may return or become more pronounced.\n\nA helpful comparison is **blood pressure medication**: its benefits generally last only as long as the medication is taken. The same applies to body weight—**biological mechanisms play a decisive role, not a lack of willpower.**\n\n## **Why do they happen at all?**\n\nThis is no coincidence, but a direct result of how GLP-1 works: it **slows gastric emptying** and acts on appetite centres in the brain. This is what helps you feel full — but it can also affect the gastrointestinal tract. That is why symptoms are often strongest at the beginning of treatment and after each dose increase, then gradually improve.\n\nFor this reason, **gradual dose escalation** is not a minor detail, but one of the most important ways to reduce side effects.\n\n## **How do you get the common side effects under control?**\n\nA great deal can be cushioned with simple measures:\n\n1. **Increase the dose gradually.** Start low, increase step by step, and if needed, stay at one dose level longer until your body has adapted.\n2. **Smaller, more frequent meals** instead of large portions.\n3. **Avoid fatty, fried and heavily spiced food** – it makes nausea worse.\n4. **Drink enough.** Enough fluid prevents constipation and dehydration (especially important with vomiting or diarrhoea).\n5. **Don’t skip meals**, and don’t lie down right after eating.\n6. **Ginger or vitamin B6** can help relieve nausea. If symptoms are more severe or persist, medication may also be considered after consulting your doctor.\n\nIf a dose increase is not well tolerated, speak to your doctor — often, simply staying on the current dose for longer is enough.",{"_uid":890,"imageFit":891,"imageNew":892,"component":662,"description":112,"mobileImage":893,"desktopImage":897},"3b1b2cae-e822-43c8-8997-e5a4d48065c5","contain",[],{"id":894,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":895,"copyright":112,"fieldtype":114,"meta_data":896,"is_external_url":20},202879211068817,"https://a.storyblok.com/f/103647/2400x1800/aea4c82311/how-do-you-get-the-common-side-effects-under-control_.png",{"size":667},{"id":894,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":895,"copyright":112,"fieldtype":114,"meta_data":898,"is_external_url":20},{"size":667},{"_uid":656,"content":900,"component":654},"## **Which side effects are rare – and when do you need to act?**\n\nLess common, but important to take seriously, are **inflammation of the pancreas (pancreatitis)**, **gallbladder problems** (such as gallstones) and — due to severe vomiting or diarrhoea — **dehydration**, which can put strain on the kidneys. People who also take other diabetes medications (such as insulin) have a higher risk of **low blood sugar (hypoglycaemia)**.\n\n**Warning signs — seek medical advice rather than waiting:**\n\n- **Severe, persistent upper abdominal pain**, possibly radiating to the back (possible sign of pancreatitis) → seek urgent medical assessment\n- **Persistent vomiting** (for around 24 hours or longer) or signs of dehydration (dark urine, dizziness)\n- **Yellowing of the skin or eyes**, or fever with abdominal pain\n- Signs of low blood sugar, such as trembling, sweating or confusion\n\nIf in doubt, always seek medical advice.\n\n## **And what about the things you read about?**\n\n- **The so-called “weight-loss face” / sagging skin:** This is usually the result of **rapid weight loss**, not the medicine itself. Losing weight more slowly and preserving muscle help.\n- **Muscle mass:** Muscle mass can also decrease during weight loss. Getting enough protein and doing targeted strength training can help preserve it as much as possible (learn more in our article on muscle and GLP-1).\n- **Mood:** there was an initial concern about suicidal thoughts with GLP-1. However, large analyses and regulators (the US FDA and the European EMA, 2024) found no established link between GLP-1 and increased suicidality risk; a systematic review reached the same conclusion \\[3- Important note here\\]. Still, if you notice changes in your mood, talk to your doctor.\n\n## **Why medical guidance reduces side effects**\n\nHow well you can manage side effects depends greatly on how the treatment is guided. Studies show that people whose dose is increased gradually experience nausea less often — and are significantly less likely to stop treatment. This is exactly where supported care makes a difference.\n\nAt *care*, this means:\n\n- The dose is increased **individually and under medical supervision**.\n- During **monthly video consultations**, symptoms and opportunities for optimisation are discussed, and the dosage is adjusted when appropriate.\n- You know **who to contact** if something comes up — instead of having to rely on Google.\n\nThis helps turn “side effects that put me off” into “symptoms that can be managed.”\n\n**Not sure whether this is right for you?** Take the no-obligation **eligibility check**. If treatment may be suitable for you, CARE’s team of FMH-certified physicians will carefully review your information with no obligation. → [**Check your eligibility**](/ch-en/tests/medical-weight-loss)",{"_uid":902,"imageFit":660,"imageNew":903,"component":662,"description":112,"mobileImage":904,"desktopImage":909},"28dd2abd-e767-4872-9cfc-354fe5bc19e8",[],{"id":905,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":906,"copyright":112,"fieldtype":114,"meta_data":907,"is_external_url":20},202879211105685,"https://a.storyblok.com/f/103647/2396x1800/d4e49f9674/why-medical-guidance-reduces-side-effects-en.png",{"size":908},"2396x1800",{"id":905,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":906,"copyright":112,"fieldtype":114,"meta_data":910,"is_external_url":20},{"size":908},{"_uid":683,"content":912,"component":654},"## **In brief**\n\nMost GLP-1 side effects are gastrointestinal symptoms — dose-dependent and temporary. With gradual dose increases, small adjustments to nutrition and fluid intake, and medical support, they can usually be managed well. It is important to recognise the rare but serious **warning signs** and act early. The goal is not “no side effects,” but side effects that are well controlled.\n\n## **Frequently asked questions**\n\n**How long do GLP-1 side effects last?** The common digestive complaints occur mainly at the start and after dose increases, and usually improve within 4 to 8 weeks as the body adjusts.\n\n**What helps best against nausea?** Increase the dose slowly, eat smaller and more frequent meals, avoid fatty and heavily spiced food, drink enough; some people find ginger or vitamin B6 helpful. For more severe complaints there are prescription medications.\n\n**Are GLP-1 medicines dangerous?** For most people they are well tolerated under medical guidance. Serious side effects are rare – what matters is knowing the warning signs and seeking medical advice when in doubt.\n\n**Do I have to stop treatment if I feel nauseous?** Not necessarily. Often it’s enough to stay on the current dose for longer or adjust your diet. This is best discussed with your doctor.\n\nYou can also read more in our our article on [stopping weight-loss injections](/ch-en/blog/articles/stopping-weight-loss-injections-what-happens-and-how-to-keep-your-result).",{"_uid":686,"title":687,"content":914,"component":689},"\\[1\\] Jalleh RJ, Talley NJ, Horowitz M, Nauck MA. The science of safety: adverse effects of GLP-1 receptor agonists as glucose-lowering and obesity medications. J Clin Invest. 2026;136(4). doi:[10.1172/JCI194740](https://doi.org/10.1172/JCI194740).\n\n\\[2\\] Comparative gastrointestinal adverse effects of GLP-1 receptor agonists and multi-target analogs in type 2 diabetes: a Bayesian network meta-analysis. Front Pharmacol. 2025. doi:[10.3389/fphar.2025.1613610](https://doi.org/10.3389/fphar.2025.1613610).\n\n\\[2\\] Association of GLP-1 Receptor Agonists With Risk of Suicidal Ideation and Behaviour: A Systematic Review and Meta-Analysis ([PMC11823376](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823376/)); the FDA (Jan 2024) and EMA-PRAC (Apr 2024) found no established link.",{"_uid":691,"content":916,"component":654},"### **Medical disclaimer**\n\n*This article is intended for general information and health education. It does not replace individual medical advice, diagnosis or treatment. Any prescription treatments mentioned are available only on a doctor’s prescription. If you have health concerns, please consult a doctor.*",[918],{"_uid":695,"title":919,"no_index":20,"og_image":697,"canonical":920,"component":235,"no_follow":20,"description":921,"image_param":237,"hide_sitemap":20},"GLP-1 Side Effects: Common, Rare & How to Manage",{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},"Which side effects GLP-1 really causes, why most are harmless, how to get nausea & co. under control – and which warning signs need a doctor.\n\n",{"name":701,"created_at":702,"published_at":703,"updated_at":704,"id":705,"uuid":706,"content":923,"slug":717,"full_slug":718,"sort_by_date":124,"position":719,"tag_list":927,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":721,"first_published_at":722,"release_id":124,"lang":130,"path":124,"alternates":928,"default_full_slug":718,"translated_slugs":931,"_stopResolving":18},{"_uid":708,"name":701,"role":709,"photo":924,"isFemale":20,"linkedin":926,"location":119,"component":120,"description":716},{"id":711,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":712,"copyright":112,"fieldtype":114,"meta_data":925,"is_external_url":20},{},{"id":112,"url":715,"linktype":186,"fieldtype":118,"cached_url":715},[],[929,930],{"id":725,"name":701,"slug":717,"published":18,"full_slug":726,"is_folder":20,"parent_id":135},{"id":728,"name":701,"slug":717,"published":18,"full_slug":729,"is_folder":20,"parent_id":139},[],{"name":100,"created_at":101,"published_at":102,"updated_at":103,"id":104,"uuid":105,"content":933,"slug":122,"full_slug":123,"sort_by_date":124,"position":125,"tag_list":937,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":128,"first_published_at":129,"release_id":124,"lang":130,"path":124,"alternates":938,"default_full_slug":123,"translated_slugs":941,"_stopResolving":18},{"_uid":107,"name":108,"role":109,"photo":934,"isFemale":18,"linkedin":936,"location":119,"component":120,"description":121},{"id":111,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":113,"copyright":112,"fieldtype":114,"meta_data":935,"is_external_url":20},{},{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},[],[939,940],{"id":133,"name":100,"slug":122,"published":18,"full_slug":134,"is_folder":20,"parent_id":135},{"id":137,"name":100,"slug":122,"published":18,"full_slug":138,"is_folder":20,"parent_id":139},[],[943],{"name":6,"created_at":744,"published_at":745,"updated_at":746,"id":747,"uuid":5,"content":944,"slug":9,"full_slug":7,"sort_by_date":124,"position":751,"tag_list":945,"is_startpage":20,"parent_id":753,"meta_data":124,"group_id":754,"first_published_at":745,"release_id":124,"lang":130,"path":124,"alternates":946,"default_full_slug":7,"translated_slugs":947,"_stopResolving":18},{"_uid":749,"title":6,"component":750},[],[],[],"The most common GLP-1 side effects affect the digestive system – nausea above all. They’re usually mild, dose-related and ease off after a few weeks. With slow dose increases and a few simple tricks, they’re manageable. Rare, serious side effects do exist – and for those, what counts is knowing the warning signs and getting them checked early.\n","2026-07-28 13:30",{"id":951,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":952,"copyright":112,"fieldtype":114,"meta_data":953,"is_external_url":20},202879211085204,"https://a.storyblok.com/f/103647/2400x1800/e90efde82f/hero-2.png",{"size":667},{"id":951,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":952,"copyright":112,"fieldtype":114,"meta_data":955,"is_external_url":20},{"size":667},"glp-1-side-effects-what-s-common-what-s-rare-and-how-to-get-them-under-control","ch-en/blog/articles/glp-1-side-effects-what-s-common-what-s-rare-and-how-to-get-them-under-control",-800,[],"dd7b05ce-f51b-4af4-bcde-916d53aaa355","2026-07-30T13:45:25.177Z",[963,968],{"id":964,"name":965,"slug":966,"published":18,"full_slug":967,"is_folder":20,"parent_id":778},202884705528878,"GLP-1-Nebenwirkungen: Was häufig ist, was selten – und wie du sie in den Griff bekommst","glp-1-nebenwirkungen-was-haeufig-ist-was-selten-ist-und-wie-du-sie-in-den-griff-bekommst","ch-de/blog/articles/glp-1-nebenwirkungen-was-haeufig-ist-was-selten-ist-und-wie-du-sie-in-den-griff-bekommst",{"id":969,"name":970,"slug":971,"published":18,"full_slug":972,"is_folder":20,"parent_id":784},202884712897583,"Effets secondaires des GLP-1 : ce qui est fréquent, ce qui est rare – et comment les maîtriser","effets-secondaires-glp-1-ce-qui-est-frequent-ce-qui-est-rare-et-comment-les-maitriser","ch-fr/blog/articles/effets-secondaires-glp-1-ce-qui-est-frequent-ce-qui-est-rare-et-comment-les-maitriser",[],{"name":975,"created_at":976,"published_at":977,"updated_at":978,"id":979,"uuid":980,"content":981,"slug":1065,"full_slug":1066,"sort_by_date":124,"position":1067,"tag_list":1068,"is_startpage":20,"parent_id":769,"meta_data":124,"group_id":1069,"first_published_at":1070,"release_id":124,"lang":130,"path":124,"alternates":1071,"default_full_slug":1066,"translated_slugs":1082},"The Top 10 Biomarkers: What They Mean and How to Act on Them","2026-07-23T16:04:09.898Z","2026-07-29T07:13:42.594Z","2026-07-29T07:13:42.613Z",201248972413430,"7618287f-e108-4ac9-87f6-4a683d031abd",{"_uid":982,"body":983,"meta":994,"title":975,"author":1000,"reviewer":1023,"component":741,"categories":1033,"description":1055,"publishedAt":1056,"heroMobileImage":1057,"heroDesktopImage":1061},"657daeff-a86d-4411-a3c8-a42935616595",[984,987,990],{"_uid":985,"content":986,"component":654},"f1b3df92-f0fa-454e-adac-9a323bf60562","## Why these ten\n\nTogether, these ten span the systems that quietly shape how you age: your heart and vessels, your metabolism, your level of inflammation, your kidney function, and your body composition. Some are names you’ll recognise; others less so — but each earns its place.\n\nWhether this is your first look at your numbers or you already follow them, the same principle applies: a single measurement is a snapshot, and the real insight comes from knowing where you stand today and watching how each marker moves over time.\n\nA quick note before we start. Most of these markers can be influenced by everyday factors — how you eat, move, sleep and recover — so throughout we’ve included both how to improve a marker that’s drifted and how to maintain one that’s already in a good range. And all of them are best read in context, with a doctor, rather than in isolation. This article is educational; it isn’t a diagnosis or medical advice.\n\nA word on testing, too: these markers are covered across ***care***’s check-ups and app-based follow-up tests — more on exactly how at the end.\n\nThis is health worth understanding well — so let’s dive in, starting at number one.\n\n## 1\\. LDL — Low-Density Lipoprotein\n\nLDL has earned a blunt reputation as the ‘artery clogger’. It is the main lipoprotein particle that carries cholesterol through your bloodstream and remains the most extensively studied lipid marker in cardiovascular research.\n\n**Why it matters.** When the number of LDL particles exceeds what your body needs for normal cell function, individual particles can enter the arterial wall. This is particularly relevant through cumulative, time-dependent exposure of the vessel wall to the lipid particle load, which promotes the development of atherosclerosis and cardiovascular risk. In some people, very high levels are genetically driven (familial hypercholesterolaemia) — an unexpectedly high value should therefore be taken seriously.\n\n**How your body actually regulates it.** The most powerful lever for lowering your LDL particle load is your own metabolism — and it is trainable. Regular Zone-2 endurance training (60–70% of maximum heart rate) increases the number and efficiency of mitochondria in your muscles. This optimises fat oxidation and has an additional effect on liver metabolism by enabling more efficient clearance of LDL particles from the circulation. Strength training amplifies this further: more muscle mass means higher energy demand and better overall fat metabolism. In short: a metabolically trained body clears circulating LDL faster than diet alone ever could.\n\n## 2\\. ApoB — Apolipoprotein B\n\nIf LDL is the headline, ApoB is the particle counter. ApoB is the structural protein present on every atherogenic lipoprotein particle — LDL, VLDL, IDL, and Lp(a). Because each of these particles carries exactly one ApoB molecule, measuring ApoB directly reflects the total number of particles capable of entering and damaging the arterial wall.\n\n**Why it matters.** Standard LDL cholesterol tests measure the *amount* of cholesterol inside the particles, not the *number* of particles themselves. These two values frequently diverge. Two people can have the same LDL cholesterol level but very different particle counts. It is the number of particles — not the cholesterol cargo — that repeatedly collides with the arterial wall, promoting atherosclerosis. For this reason, ApoB is increasingly regarded as a more precise marker of cardiovascular risk than LDL cholesterol alone, especially in people with metabolic syndrome, insulin resistance, high triglycerides, or elevated Lp(a).\n\n**How your body actually regulates it.** Like LDL, ApoB is driven mostly by your metabolism rather than diet alone. Consistent Zone-2 endurance training sharpens your liver’s ability to clear ApoB-containing particles from your blood, while burning the visceral fat that fuels their production in the first place — less fat reaching the liver means fewer particles made. Strength training compounds this: more muscle raises your energy demand and improves how your body handles fats overall. Diet still matters (especially cutting saturated fat and adding soluble fibre), but the long-term drivers are steady aerobic training, visceral fat loss, and holding on to muscle.\n\n## 3\\. Lp(a) — Lipoprotein(a)\n\nLp(a) is largely inherited — set in your DNA. It’s genetically determined and stays relatively stable throughout adult life.\n\n**Why it matters.** Lp(a) is an LDL-like particle with an extra protein attached (apolipoprotein(a)). Elevated levels are independently associated with increased risk of atherosclerotic cardiovascular disease, including heart attack and stroke. Because elevated levels are common (roughly 20–30% of people have significant levels) and cause no symptoms, most people with it don’t know. A one-time test in adulthood is valuable: it can uncover a lifelong, otherwise hidden risk factor and help explain family patterns of early cardiovascular disease.\n\n**What you can actually change.** Unlike LDL cholesterol or ApoB, Lp(a) is only minimally modifiable through lifestyle, diet, or standard lipid-lowering therapies. Its value lies mainly in risk stratification rather than direct treatment. If Lp(a) is elevated, the focus shifts to managing all other modifiable risk factors more aggressively (LDL/ApoB, blood pressure, glucose metabolism, inflammation, smoking, and visceral fat). In people with very high Lp(a) plus other risk factors, guideline-directed intensification of LDL-lowering therapy is currently the best-supported approach to reduce overall atherogenic burden. Specific Lp(a)-lowering therapies are in advanced clinical development but not yet routinely available.\n\n**Bottom line:** get Lp(a) tested at least once. A high result doesn’t change what you can do about Lp(a) itself — but it should change how aggressively you approach everything else that is modifiable.\n\n## 4\\. Blood Pressure\n\nBlood pressure is reported as two numbers — systolic (pressure when your heart contracts) over diastolic (pressure when your heart relaxes) — and reflects the force blood exerts against your artery walls. It’s one of the most important vital signs and a major driver of long-term cardiovascular and kidney health.\n\n**Why it matters.** Sustained high blood pressure places continuous mechanical stress on arteries, the heart, brain, kidneys, and eyes. This “silent” damage often builds over years without noticeable symptoms, gradually contributing to atherosclerosis, heart failure, stroke, and/or kidney disease. Because hypertension is one of the most modifiable cardiovascular risk factors, regular measurement is key to catching it early and preventing complications.\n\n**A note on measurement, honestly.** A single measurement can be influenced by stress. A representative profile therefore requires several readings. Factors linked to blood pressure include body weight, physical activity, recovery deficit and stimulant substances.\n\n## 5\\. HbA1c — Long-Term Blood Sugar\n\nHbA1c measures the percentage of haemoglobin that has glucose attached to it. Because red blood cells live about 120 days, HbA1c gives an integrated picture of average blood sugar over the past 8–12 weeks.\n\n**Why it matters.** It’s the standard marker for assessing long-term glucose control and for identifying prediabetes or diabetes. Elevated HbA1c reflects chronic hyperglycaemia and is strongly linked to microvascular complications (eyes, kidneys, nerves) and macrovascular risk (heart attack, stroke). Its biggest value is catching early, still-reversible stages of glucose dysregulation before full diabetes develops.\n\n**Important caveats.** HbA1c is not reliable in conditions that alter red-cell lifespan or turnover (e.g. anaemia, recent blood loss or pregnancy). In such cases it should be interpreted together with fasting glucose.\n\n**How to influence it.** HbA1c responds sensitively to sustained lifestyle changes: regular activity (especially Zone-2 training below the anaerobic threshold), weight or visceral-fat reduction, a lower glycaemic-index diet, and balanced load/recovery management. Pharmacological support (e.g. metformin) is often added when lifestyle alone is insufficient. Because the value reflects a 2–3-month window, meaningful changes usually become visible only after 8–12 weeks of consistent measures.\n\n## 6\\. Fasting Glucose\n\nFasting glucose measures blood sugar after at least 8 hours without caloric intake — a snapshot of your liver’s glucose output and baseline insulin sensitivity.\n\n**Why it matters.** It helps identify impaired fasting glucose and diabetes. Interpreted alongside HbA1c, it gives a fuller picture: HbA1c shows the trend, fasting glucose shows the current baseline. An elevated fasting glucose often signals early hepatic insulin resistance.\n\n**One reading doesn’t tell the whole story.** A single elevated result can stem from acute stress, poor sleep, illness, or medications. Diagnosis requires confirmation on a separate day unless classic symptoms are present.\n\n**How to influence it.** Improvements come primarily from reducing visceral fat, building muscular metabolic capacity through strength/resistance training, Zone-2 endurance training for effective glucose buffering, and a low-glycaemic-index diet. These measures improve insulin sensitivity and curb excessive hepatic glucose production.\n\n## 7\\. Kidney Function — Creatinine\n\nCreatinine is a waste product of muscle metabolism. Its serum level, combined with age, sex, and in some formulas ethnicity, is used to estimate glomerular filtration rate (eGFR) — the best routinely available indicator of kidney function.\n\n**Why it matters.** The kidneys filter blood continuously and silently. A declining eGFR often produces no symptoms until advanced stages. Because high blood pressure, diabetes, and metabolic syndrome are leading causes of chronic kidney disease, regular eGFR monitoring rounds out the cardiometabolic picture.\n\n**Important context.** Creatinine (and therefore eGFR) is heavily influenced by muscle mass, protein intake, creatine supplementation, hydration, and age. In muscular or athletic individuals, creatinine-based eGFR can underestimate true kidney function; cystatin-C-based eGFR is often more accurate in these cases.\n\n**How to influence it.** Kidney health is mostly supported indirectly: through excellent long-term blood pressure and glucose control, a healthy body composition, adequate hydration, and avoiding chronic use of nephrotoxic medications (e.g. NSAIDs).\n\n## 8\\. Visceral Fat\n\nVisceral fat is the metabolically active fat stored deep in the abdominal cavity, around your internal organs, distinct from subcutaneous fat just under the skin.\n\n**Why it matters.** Unlike subcutaneous fat, visceral fat releases free fatty acids and pro-inflammatory signals. It’s strongly linked to insulin resistance, fatty liver disease (MAFLD), dyslipidemia, high blood pressure, and elevated cardiovascular risk — even in people who don’t look overweight (the “TOFI” phenotype: thin outside, fat inside).\n\n**How to influence it.** Visceral fat is among the most responsive fat stores to intervention. It’s most effectively reduced through a combination of caloric deficit, regular Zone-2 endurance training (most effective for fat oxidation), strength training (improves muscle’s metabolic capacity), stress reduction, and adequate recovery. Improvements in visceral fat simultaneously deliver metabolic benefits.\n\n## 9\\. hs-CRP — High-Sensitivity C-Reactive Protein\n\nhs-CRP is a sensitive marker of systemic, low-grade inflammation, produced by the liver in response to inflammatory signals (particularly IL-6).\n\n**Why it matters.** Chronic low-grade inflammation plays a central role in the development and progression of atherosclerosis. Elevated hs-CRP is independently associated with increased cardiovascular risk, sometimes even when cholesterol looks normal. It adds an inflammatory dimension to risk assessment.\n\n**Important caveats.** hs-CRP is non-specific. A recent infection, injury, intense exercise, or inflammatory conditions can cause temporary spikes. It should be interpreted in clinical context and ideally measured in a stable state.\n\n**How to influence it.** Lifestyle levers that reliably lower hs-CRP include reducing visceral fat, regular moderate exercise, an anti-inflammatory, Mediterranean-style diet, avoiding smoking, adequate sleep, and stress reduction. Treating underlying inflammatory conditions (e.g. gum disease, autoimmune conditions) matters too.\n\n## 10\\. Omega-3 Index\n\nThe Omega-3 Index measures the percentage of EPA + DHA in red blood cell membranes and reflects long-term omega-3 fatty acid status (roughly 3–4 months).\n\n**Why it matters.** A higher Omega-3 Index (≥4.5%, ideally ≥8%) is associated with anti-inflammatory capacity and thereby with a lower risk of cardiovascular events.\n\n**How to influence it.** The index responds reliably to increased intake of EPA and DHA from fatty fish (salmon, mackerel, sardines) or quality supplements (fish or algae oil). Aim for 1–2g combined EPA+DHA daily for maintenance, higher doses for specific indications only under medical guidance.",{"_uid":988,"content":989,"component":654},"a9d6e9ca-5e36-4dd5-86d4-616641d1b5dd","## Bringing it together\n\nKnowing your numbers is the first step. What each of these ten markers offers on its own is a starting point — but the real picture comes from reading them together, and from watching how they move.\n\nThey also talk to each other. Visceral fat can nudge glucose and inflammation; lipids and inflammation compound each other’s effect on your arteries; blood pressure and kidney function are closely tied. Seen side by side, patterns emerge that no single value would reveal — which is why the ten are more useful as a panel than as ten separate facts.\n\nThat’s where following them over time matters. A single check-up tells you where you stand today; a second one shows you the direction of travel — which markers are settling into a good range, and which might need more attention. How often to re-test depends on the marker and on you: something like Lp(a) is largely a once-in-a-lifetime number, while the modifiable markers are worth revisiting periodically so you can see whether a change you’ve made is actually landing. Think of your ***care*** App as your health’s best friend — always in your pocket, keeping all your results in one place so you see the trend, not just the snapshot. It’s also where, as a customer, you can add markers over time through follow-up tests you book directly in the App, including ones like the Omega-3 Index.\n\nThis is exactly why interpretation together with a doctor is at the heart of meaningful health insights. These markers do not exist in isolation — they interact, and individual results always require context. What is “normal” or actionable for one person may differ for another. A ***care*** physician helps you connect the dots, identify what is truly relevant for your personal situation, and decide on the most effective next steps — whether that means lifestyle adjustments, further testing, or medical therapy.\n\n### See where you stand\n\nAt ***care***, the full-body check-up is the most comprehensive way to view these markers together — more than 100 biomarkers in around 20 minutes, plus body-composition analysis, blood parameters and a blood-pressure measurement. Epigenetic biomarkers are covered through our additional check-ups and app-based follow-up tests — nothing remains out of reach.\n\nWhichever you start with, your results are structured clearly in the ***care*** App and come with a personalized medical report and concrete recommendations from your doctor.\n\n[**Book your check-up**](https://booking.care.me/ch-en/check-up/)\n\nAlready a ***care*** customer? Head to the services page in your ***care*** App to book your follow-up and any app-exclusive tests, then track your markers over time.\n\n*This article is for educational purposes and does not replace individual medical advice. Your biomarker results are best interpreted with your **care** doctor, who can place them in the context of your personal health.*",{"_uid":991,"title":992,"content":993,"component":689},"2c58cee2-1da9-41e2-adf0-0994f5d90cb3","References"," 1. Mhaimeed et al. (2024). The importance of LDL-C lowering in atherosclerotic cardiovascular disease. PubMed: PMID 38576462. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/38576462/>\n 2. Peng et al. (2022). Association of low-density lipoprotein cholesterol levels with the risk of mortality and cardiovascular events. Meta-analysis, >1.2 million participants. PubMed: PMID 36482567. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/36482567/>\n 3. Sniderman et al. (2019). Apolipoprotein B particles and cardiovascular disease: a narrative review. PubMed: PMID 31642874. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/31642874/>\n 4. Glavinovic et al. (2022). Physiological bases for the superiority of apolipoprotein B over LDL-C. PubMed: PMID 36216435. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/36216435/>\n 5. Sniderman et al. (2011). A meta-analysis of low-density lipoprotein cholesterol, non-HDL-C, and apolipoprotein B. PubMed: PMID 21487090. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/21487090/>\n 6. Lau et al. (2022). Lipoprotein(a) and its significance in cardiovascular disease: a review. PubMed: PMID 35583875. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/35583875/>\n 7. Tasdighi et al. (2024). Lp(a): structure, genetics, associated cardiovascular risk, and emerging therapeutics. PubMed: PMID 37506332. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/37506332/>\n 8. Greco et al. (2025). Lipoprotein(a) as a pharmacological target. PubMed: PMID 39928714. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/39928714/>\n 9. Fuchs et al. (2020). High blood pressure and cardiovascular disease. PubMed: PMID 31865786. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/31865786/>\n10. Kjeldsen et al. (2018). Hypertension and cardiovascular risk: general aspects. PubMed: PMID 29127059. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/29127059/>\n11. Baffour, Jahangiry, Jain, Sen & Aune (2024). Blood pressure, hypertension, and the risk of heart failure. Meta-analysis. PubMed: PMID 37939784. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/37939784/>\n12. Mehta, Blumenthal, Gluckman, Feldman & Kohli (2025). High-sensitivity C-reactive protein in atherosclerotic cardiovascular disease. PubMed: PMID 40171210. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/40171210/>\n13. Brannick et al. (2018). Prediabetes and cardiovascular disease: pathophysiology and review of the current literature. PMC: PMC5806140. Link: \u003Chttps://pmc.ncbi.nlm.nih.gov/articles/PMC5806140/>\n14. Yahyavi et al. (2021). Prediabetes defined by first measured HbA1c predicts higher cardiovascular risk. PubMed: PMID 34675054. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/34675054/>\n15. Després et al. (2012). Body fat distribution and risk of cardiovascular disease. Landmark paper. AHA: PMID 22949540. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/22949540/>\n16. Cesaro et al. (2023). Visceral adipose tissue and residual cardiovascular risk. PMC: PMC10421666. Link: \u003Chttps://pmc.ncbi.nlm.nih.gov/articles/PMC10421666/>\n17. Silveira et al. (2020). Visceral obesity and incident cancer and cardiovascular disease. PMC: PMC7757158. Link: \u003Chttps://pmc.ncbi.nlm.nih.gov/articles/PMC7757158/>\n18. Bassuk & Ridker (2004). High-sensitivity C-reactive protein: clinical importance. PubMed: PMID 15258556. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/15258556/>\n19. Banait et al. (2022). Role of high-sensitivity C-reactive protein (hs-CRP) in non-communicable diseases. PMC: PMC9650935. Link: \u003Chttps://pmc.ncbi.nlm.nih.gov/articles/PMC9650935/>\n20. High-sensitivity C-reactive protein in atherosclerotic cardiovascular disease (2025). PubMed: PMID 40171210. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/40171210/>\n21. Harris & von Schacky (2004). The omega-3 index: a new risk factor for death from coronary heart disease? Original paper. PubMed: PMID 15208005. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/15208005/>\n22. von Schacky (2014). Omega-3 index and cardiovascular health. PMC: PMC3942733. Link: \u003Chttps://pmc.ncbi.nlm.nih.gov/articles/PMC3942733/>\n23. Harris (2025). Recent studies confirm the utility of the omega-3 index. PubMed: PMID 39514368. Link: \u003Chttps://pubmed.ncbi.nlm.nih.gov/39514368/>",[995],{"_uid":996,"title":997,"no_index":20,"og_image":112,"canonical":998,"component":235,"no_follow":20,"description":999,"image_param":237,"hide_sitemap":20},"cc573995-7d48-4536-bc3b-132374b1c676","Top 10 Biomarkers: What They Mean & How to Improve Them",{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},"care's doctors rank the ten biomarkers that matter most for your health today - and how to improve each one, as early as possible.",{"name":1001,"created_at":1002,"published_at":1003,"updated_at":1004,"id":1005,"uuid":1006,"content":1007,"slug":1015,"full_slug":1016,"sort_by_date":124,"position":1017,"tag_list":1018,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":1019,"first_published_at":1020,"release_id":124,"lang":130,"path":124,"alternates":1021,"default_full_slug":1016,"translated_slugs":1022,"_stopResolving":18},"Greta Werner","2026-07-23T15:38:35.732Z","2026-08-03T13:17:36.745Z","2026-08-03T13:17:36.779Z",201242688472785,"fc35acce-eeff-4f6c-9be2-c81405ad83db",{"_uid":107,"name":1001,"role":1008,"photo":1009,"isFemale":18,"linkedin":1013,"location":119,"component":120,"description":1014},"Marketer",{"id":1010,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1011,"copyright":112,"fieldtype":114,"meta_data":1012,"is_external_url":20},201246801321588,"https://a.storyblok.com/f/103647/1374x1145/4cd3eecfa9/chatgpt-image-jul-23-2026-05_28_19-pm.png",{},{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},"Greta is a Marketer at CARE, helping translate the latest research into clear, actionable health content.","greta-werner","ch-en/blog/authors/greta-werner",-30,[],"2f218cbd-e565-44bd-8312-cf8ffc6b1e00","2026-07-24T16:08:16.777Z",[],[],{"name":100,"created_at":101,"published_at":102,"updated_at":103,"id":104,"uuid":105,"content":1024,"slug":122,"full_slug":123,"sort_by_date":124,"position":125,"tag_list":1028,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":128,"first_published_at":129,"release_id":124,"lang":130,"path":124,"alternates":1029,"default_full_slug":123,"translated_slugs":1032,"_stopResolving":18},{"_uid":107,"name":108,"role":109,"photo":1025,"isFemale":18,"linkedin":1027,"location":119,"component":120,"description":121},{"id":111,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":113,"copyright":112,"fieldtype":114,"meta_data":1026,"is_external_url":20},{},{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},[],[1030,1031],{"id":133,"name":100,"slug":122,"published":18,"full_slug":134,"is_folder":20,"parent_id":135},{"id":137,"name":100,"slug":122,"published":18,"full_slug":138,"is_folder":20,"parent_id":139},[],[1034],{"name":25,"created_at":1035,"published_at":1036,"updated_at":1035,"id":1037,"uuid":24,"content":1038,"slug":32,"full_slug":26,"sort_by_date":124,"position":1040,"tag_list":1041,"is_startpage":20,"parent_id":753,"meta_data":124,"group_id":1042,"first_published_at":1043,"release_id":124,"lang":130,"path":124,"alternates":1044,"default_full_slug":26,"translated_slugs":1054,"_stopResolving":18},"2023-12-11T15:38:36.855Z","2023-12-22T00:43:01.000Z",417185141,{"_uid":1039,"title":25,"component":750},"6c953c7a-9e39-4974-ac2f-2b2a41bf3edc",-40,[],"8d78d0dc-3a55-4595-a90c-ac07b66529f8","2023-09-07T08:47:26.294Z",[1045,1049,1050],{"id":1046,"name":25,"slug":32,"published":20,"full_slug":1047,"is_folder":20,"parent_id":1048},371296522,"archive/blog/categories/general-health",359960850,{"id":29,"name":25,"slug":30,"published":18,"full_slug":31,"is_folder":20,"parent_id":21},{"id":1051,"name":25,"slug":32,"published":20,"full_slug":1052,"is_folder":20,"parent_id":1053},417185142,"archive/us-en/blog/categories/general-health",417185120,[],"CARE's doctors have ranked the ten biomarkers they consider most important for everyone to test and gain clarity on — the core, measurable determinants that reflect your health today and help predict where it's heading. This is a closer look at each: what it tells you, and how to improve it where you can, as early as you can.","2026-07-23 00:00",{"id":1058,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1059,"copyright":112,"fieldtype":114,"meta_data":1060,"is_external_url":20},201246734286445,"https://a.storyblok.com/f/103647/1200x1600/1cd665af89/hero-mobile.png",{},{"id":1062,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1063,"copyright":112,"fieldtype":114,"meta_data":1064,"is_external_url":20},201246734302830,"https://a.storyblok.com/f/103647/2800x2000/9890070218/hero-desktop.png",{},"the-top-10-biomarkers-what-they-mean-and-how-to-act-on-them","ch-en/blog/articles/the-top-10-biomarkers-what-they-mean-and-how-to-act-on-them",-1000,[],"3e921012-652c-4f18-9e7a-8ad37fc202b3","2026-07-24T08:10:09.893Z",[1072,1077],{"id":1073,"name":1074,"slug":1075,"published":18,"full_slug":1076,"is_folder":20,"parent_id":778},201259659725255,"Die Top 10 Biomarker: Was sie bedeuten – und wie du sie gezielt beeinflusst","die-top-10-biomarker-was-sie-bedeuten-und-wie-du-sie-gezielt-beeinflusst","ch-de/blog/articles/die-top-10-biomarker-was-sie-bedeuten-und-wie-du-sie-gezielt-beeinflusst",{"id":1078,"name":1079,"slug":1080,"published":18,"full_slug":1081,"is_folder":20,"parent_id":784},201489708368217,"Les 10 biomarqueurs essentiels : ce qu'ils signifient et comment agir","les-10-biomarqueurs-essentiels-ce-qu-ils-signifient-et-comment-agir","ch-fr/blog/articles/les-10-biomarqueurs-essentiels-ce-qu-ils-signifient-et-comment-agir",[],{"name":1084,"created_at":1085,"published_at":1086,"updated_at":1087,"id":1088,"uuid":1089,"content":1090,"slug":1168,"full_slug":1169,"sort_by_date":124,"position":1170,"tag_list":1171,"is_startpage":20,"parent_id":769,"meta_data":124,"group_id":1172,"first_published_at":1173,"release_id":124,"lang":130,"path":124,"alternates":1174,"default_full_slug":1169,"translated_slugs":1185},"Muscle, Not Just Kilos: Why Body Composition Matters When You Lose Weight on GLP-1","2026-07-10T08:47:47.462Z","2026-08-18T19:48:54.979Z","2026-08-18T19:48:54.998Z",196541101964060,"fbf9d11d-b679-4668-b802-2ca20934656d",{"_uid":649,"body":1091,"meta":1127,"title":1084,"author":1132,"reviewer":1142,"component":741,"categories":1152,"description":1158,"publishedAt":1159,"heroMobileImage":1160,"heroDesktopImage":1164},[1092,1094,1096,1106,1108,1111,1121,1123,1125],{"_uid":652,"content":1093,"component":654},"## **The three things to remember**\n\n- Part of the weight you lose is fat-free mass (including muscle) — in studies, roughly **20–30%**. At the same time, the ratio of muscle to fat often improves.\n- Preserving your muscle mass is l**argely in your hands**: regular strength training and adequate protein intake make the difference.\n- That's why **how** you lose weight matters—and the only way to see it is through your body composition.\n\nThe scale shows you just one number—but it doesn't tell you whether you've lost fat or muscle. And that's the crucial difference when losing weight with GLP-1 medication: losing weight is not the same as losing **metabolically active tissue**.\n\nThis article looks at where things stand with **muscle loss on GLP-1**, what the research says — and, above all, what you can do yourself so that in the end you lose mainly fat and keep your muscle.\n\n## **Do you lose muscle when you lose weight on GLP-1?**\n\nYes, to some extent. Whenever you lose weight—whether through dieting, surgery, or GLP-1 medication—part of that weight loss comes from fat-free mass, which includes muscle. Analyses of GLP-1 studies suggest that roughly 20–30% of the weight lost comes from fat-free mass.\n\n**Two key points:**\n\n**First, the overall balance often improves.** In the DXA body composition analysis from the STEP 1 trial, fat-free mass decreased by around 10%, but its proportion of total body weight increased slightly because participants lost substantially more body fat. In other words, the body became leaner overall—not proportionally \"less muscular.\"\n\n**Second, muscle loss depends more on your behaviour than on the medication itself.** And that's where you can make the biggest difference.\n\n## **Why does muscle mass matter so much in the first place?**\n\nMuscle is your body's **metabolic engine**: the more muscle mass you have, the more energy your body burns—even at rest. If you lose a significant amount of muscle, your resting metabolic rate decreases, making it harder to maintain your weight. This is one of the reasons why crash diets often lead to the yo-yo effect.\n\nMuscle also supports everyday strength, mobility, bone health, and—especially from midlife onwards—helps protect against age-related muscle loss. Low skeletal muscle mass has been associated with an approximately **57% higher risk of all-cause mortality**. Preserving your muscle mass is therefore one of the most important factors for achieving lasting weight-loss results.\n\n## **The good news: keeping muscle is largely in your hands**\n\nHere's the part that headlines often leave out: **how much muscle mass you preserve is largely up to you**—through your nutrition and training. The scientific evidence is clear.\n\nRecent reviews (2025) show that people who combine GLP-1 treatment with **strength training** and **adequate protein intake** can significantly reduce the amount of muscle mass they lose compared with simply eating less.\n\nThe medication reduces your appetite—but preserving your muscles depends on what you eat and how you move.",{"_uid":656,"content":1095,"component":654},"## **How much protein — and what kind of training?**\n\n**Two key strategies—both strongly supported by scientific evidence:**\n\n**Protein.** During weight loss, your body needs more protein than usual to preserve muscle mass. Current recommendations for people receiving GLP-1 therapy are around **1.2 to 1.6 grams of protein per kilogram of body weight per day**—with the higher end of the range being particularly appropriate during weight loss. In practice, this means aiming for **20–40 g of protein per meal**, spread throughout the day. Good sources include Greek yogurt or cottage cheese, eggs, legumes, fish, poultry, and tofu.\n\nOne challenge is that GLP-1 medications reduce appetite—precisely when many people find it hardest to eat enough protein. This is where a clear nutrition plan (and sometimes targeted supplementation) can make a real difference.\n\n**Strength training.** A high-protein diet alone is not enough—muscle is best preserved when adequate protein is combined with regular strength training. General recommendations are **at least 2–3 strength-training sessions per week**, complemented by aerobic exercise (around **150 minutes per week** as a guideline). You don't need to become a bodybuilder—even regular training with your own body weight, resistance bands, or dumbbells can make a significant difference.\n\n### ",{"_uid":659,"imageFit":660,"imageNew":1097,"component":662,"description":112,"mobileImage":1098,"desktopImage":1102},[],{"id":1099,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1100,"copyright":112,"fieldtype":114,"meta_data":1101,"is_external_url":20},197678656166254,"https://a.storyblok.com/f/103647/1200x1600/d0eeb21427/protein-training-mobile.png",{},{"id":1103,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1104,"copyright":112,"fieldtype":114,"meta_data":1105,"is_external_url":20},197678656239983,"https://a.storyblok.com/f/103647/2800x2000/bdb05a6e84/protein-training-desktop.png",{},{"_uid":671,"content":1107,"component":654},"## Metabolically active tissues\n\nIf you only focus on the number on the scale, you miss the part that matters most. Losing 6 kilograms can mean **6 kilograms of body fat** (great)—or **4 kilograms of fat and 2 kilograms of muscle** (not so great). The number is the same, but what lies behind it is completely different.\n\nWhat really matters is your **body composition**: how much fat you're losing and how much muscle mass you're preserving. A muscle and fat analysis makes this visible. It turns *\"I hope I'm doing it right\"* into *\"I can see it in black and white.\"* That not only boosts motivation—it also allows you to adjust your approach early if you're losing too much muscle.",{"_uid":1109,"content":1110,"component":654},"7b35fbd9-c75f-4483-aef3-cb9c568763ea","## **How *care* supports your body composition**\n\nThat’s exactly why a **muscle and fat analysis** is an integral part of treatment at *care*—not just once, but every month:\n\n- **Your starting point:** An initial assessment establishes your baseline body composition.\n- **Monthly body composition analysis:** Each month, your body composition is measured, distinguishing between fat and muscle—not just your weight.\n- **Medical video consultation:** Your results are reviewed with a physician, including adjustments to your nutrition and exercise plan, management of side effects, and, if needed, changes to your medication dosage.\n- **Progress tracking in the App:** You can follow your body composition over time and see whether you’re moving in the right direction.\n\nThis way, the focus isn’t simply on the number on the scale, but on achieving sustainable results—with medical guidance every step of the way.\n\n**Want to know where you stand — and whether a supported treatment fits you?** Take the no-obligation **eligibility check**. If you’re eligible, *care*’s FMH medical team reviews your details — medically checked, no pressure. → [**Check your eligibility**](/ch-en/tests/medical-weight-loss)",{"_uid":674,"imageFit":660,"imageNew":1112,"component":662,"description":112,"mobileImage":1113,"desktopImage":1117},[],{"id":1114,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1115,"copyright":112,"fieldtype":114,"meta_data":1116,"is_external_url":20},197678655568227,"https://a.storyblok.com/f/103647/1200x1600/32bbf95be8/care-desktop-en-1.png",{},{"id":1118,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1119,"copyright":112,"fieldtype":114,"meta_data":1120,"is_external_url":20},197678655801703,"https://a.storyblok.com/f/103647/2800x2000/47602a96a4/care-desktop-en.png",{},{"_uid":683,"content":1122,"component":654},"## **In brief**\n\nWhen losing weight with GLP-1 medication, you also lose some muscle mass—but **how much** is largely up to you. Getting enough protein and doing regular strength training are the two most important factors, and tracking your **body composition** makes all the difference. Measuring it regularly and reviewing the results with a physician helps you preserve muscle and achieve lasting success.\n\n## **Frequently asked questions**\n\n**Do you inevitably lose muscle on GLP-1?** Part of the weight you lose is fat-free mass, but the muscle loss can be sharply limited with protein and resistance training. In studies that included training and adequate protein, muscle loss was correspondingly small.\n\n**How much protein should I eat per day?** As a guideline, around 1.2–1.6 g per kilogram of body weight per day — toward the upper end while losing weight — ideally spread across several meals. Your individual amount is something your doctor will discuss with you.\n\n**Is protein alone enough to keep muscle?** **No.** Regular strength training (around **2–3 times per week**) is essential.\n\n**Why does *care* measure muscle-fat analysis every month?** Monthly measurements make your progress visible and allow your treatment to be adjusted when needed.",{"_uid":686,"title":687,"content":1124,"component":689},"\\[1\\] Wilding JPH, et al. *Once-weekly semaglutide in adults with overweight or obesity (STEP 1).* N Engl J Med. 2021;384(11):989–1002. doi:[10.1056/NEJMoa2032183](https://doi.org/10.1056/NEJMoa2032183).\n\n\\[2\\] Low skeletal muscle mass index and all-cause mortality risk in adults: a systematic review and meta-analysis of prospective cohort studies. PLOS One. 2023. doi:[10.1371/journal.pone.0286745](https://doi.org/10.1371/journal.pone.0286745).",{"_uid":691,"content":1126,"component":654},"### \n\n### **Medical disclaimer**\n\n*This article is intended for general information and health education. It does not replace individual medical advice, diagnosis or treatment. Any prescription treatments mentioned are available only on a doctor’s prescription. If you have health concerns, please consult a doctor.*",[1128],{"_uid":695,"title":1129,"no_index":20,"og_image":697,"canonical":1130,"component":235,"no_follow":20,"description":1131,"image_param":237,"hide_sitemap":20},"GLP-1 & Muscle Loss: Body Composition, Not Just Scale",{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},"Do you lose muscle on GLP-1? What the studies show, how protein and training help you keep muscle — and why body composition matters more than the scale.\n\n",{"name":701,"created_at":702,"published_at":703,"updated_at":704,"id":705,"uuid":706,"content":1133,"slug":717,"full_slug":718,"sort_by_date":124,"position":719,"tag_list":1137,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":721,"first_published_at":722,"release_id":124,"lang":130,"path":124,"alternates":1138,"default_full_slug":718,"translated_slugs":1141,"_stopResolving":18},{"_uid":708,"name":701,"role":709,"photo":1134,"isFemale":20,"linkedin":1136,"location":119,"component":120,"description":716},{"id":711,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":712,"copyright":112,"fieldtype":114,"meta_data":1135,"is_external_url":20},{},{"id":112,"url":715,"linktype":186,"fieldtype":118,"cached_url":715},[],[1139,1140],{"id":725,"name":701,"slug":717,"published":18,"full_slug":726,"is_folder":20,"parent_id":135},{"id":728,"name":701,"slug":717,"published":18,"full_slug":729,"is_folder":20,"parent_id":139},[],{"name":100,"created_at":101,"published_at":102,"updated_at":103,"id":104,"uuid":105,"content":1143,"slug":122,"full_slug":123,"sort_by_date":124,"position":125,"tag_list":1147,"is_startpage":20,"parent_id":127,"meta_data":124,"group_id":128,"first_published_at":129,"release_id":124,"lang":130,"path":124,"alternates":1148,"default_full_slug":123,"translated_slugs":1151,"_stopResolving":18},{"_uid":107,"name":108,"role":109,"photo":1144,"isFemale":18,"linkedin":1146,"location":119,"component":120,"description":121},{"id":111,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":113,"copyright":112,"fieldtype":114,"meta_data":1145,"is_external_url":20},{},{"id":112,"url":112,"linktype":117,"fieldtype":118,"cached_url":112},[],[1149,1150],{"id":133,"name":100,"slug":122,"published":18,"full_slug":134,"is_folder":20,"parent_id":135},{"id":137,"name":100,"slug":122,"published":18,"full_slug":138,"is_folder":20,"parent_id":139},[],[1153],{"name":6,"created_at":744,"published_at":745,"updated_at":746,"id":747,"uuid":5,"content":1154,"slug":9,"full_slug":7,"sort_by_date":124,"position":751,"tag_list":1155,"is_startpage":20,"parent_id":753,"meta_data":124,"group_id":754,"first_published_at":745,"release_id":124,"lang":130,"path":124,"alternates":1156,"default_full_slug":7,"translated_slugs":1157,"_stopResolving":18},{"_uid":749,"title":6,"component":750},[],[],[],"When losing weight with GLP-1 medication, you don't just lose fat—you also lose some muscle mass. How much muscle you preserve depends primarily on strength training, not on the medication itself. If you only focus on the number on the scale, you'll miss what matters most: your body composition.\n\n","2026-07-06 09:00",{"id":1161,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1162,"copyright":112,"fieldtype":114,"meta_data":1163,"is_external_url":20},197678655854952,"https://a.storyblok.com/f/103647/1200x1600/31dec58f42/hero-mobile-2.png",{},{"id":1165,"alt":112,"name":112,"focus":112,"title":112,"source":112,"filename":1166,"copyright":112,"fieldtype":114,"meta_data":1167,"is_external_url":20},197678656252272,"https://a.storyblok.com/f/103647/2800x2000/f41590d1e8/hero-desktop-2.png",{},"muscle-not-just-kilos-why-body-composition-matters-when-you-lose-weight-on-glp-1","ch-en/blog/articles/muscle-not-just-kilos-why-body-composition-matters-when-you-lose-weight-on-glp-1",-840,[],"6fbe4416-ca6c-46ab-89cb-ff407d8735b5","2026-07-13T14:02:44.870Z",[1175,1180],{"id":1176,"name":1177,"slug":1178,"published":18,"full_slug":1179,"is_folder":20,"parent_id":778},196542953237537,"Muskeln statt nur Kilos: Warum die Körperzusammensetzung beim Abnehmen mit GLP-1 entscheidend ist","muskeln-statt-nur-kilos-warum-die-korperzusammensetzung-beim-abnehmen-mit-glp-1-entscheidend-ist","ch-de/blog/articles/muskeln-statt-nur-kilos-warum-die-korperzusammensetzung-beim-abnehmen-mit-glp-1-entscheidend-ist",{"id":1181,"name":1182,"slug":1183,"published":18,"full_slug":1184,"is_folder":20,"parent_id":784},196544123993524,"Du muscle, pas seulement des kilos : pourquoi la composition corporelle compte quand on perd du poids avec un GLP-1","du-muscle-pas-seulement-des-kilos-pourquoi-la-composition-corporelle-compte-quand-on-perd-du-poids-avec-un-glp-1","ch-fr/blog/articles/du-muscle-pas-seulement-des-kilos-pourquoi-la-composition-corporelle-compte-quand-on-perd-du-poids-avec-un-glp-1",[],{"all":1187,"weight-loss":1194,"general-health":1196},[1188],[1189,1190,1191,1192,1193],["Reactive",641],["Reactive",786],["Reactive",878],["Reactive",974],["Reactive",1083],[1195],[1189,1190,1191,1193],[1197],[1192],1787666107608]